Chitosan and Aloe Vera Decorated Nanoparticulate System Loaded With Minoxidil as a Suggested Topical Formulation for Alopecia Therapy

    April 2023 in “ Advances in Natural Sciences: Nanoscience and Nanotechnology ”
    Ebtesam A Mohamad, Amany M Gad, Rana H Abd El-Rhman, Mirhane M Darwish
    Studysummary The new formulation with minoxidil, chitosan, and Aloe vera improves hair growth and reduces side effects.
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    Research cited in this study 13

    1. A Randomized, Double-Blind Controlled Clinical Study to Evaluate the Efficacy and Safety of Minoxidil Topical 2% Nanosuspension with Aqueous Base in the Treatment of Androgenetic Alopecia Areata Journal of reports in pharmaceutical sciences · 2021
    2. Drug Delivery System Based On Minoxidil Nanoparticles Promotes Hair Growth In C57BL/6 Mice International Journal of Nanomedicine · 2019
    3. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    4. Minoxidil Skin Delivery from Nanoemulsion Formulations Containing Eucalyptol or Oleic Acid: Enhanced Diffusivity and Follicular Targeting Pharmaceutics · 2018
    5. Potential Synergistic Effects of Human Placental Extract and Minoxidil on Hair Growth-Promoting Activity in C57BL/6J Mice Clinical and Experimental Dermatology · 2015
    6. Chitosan Nanoparticles for Targeting and Sustaining Minoxidil Sulphate Delivery to Hair Follicles International Journal of Biological Macromolecules · 2015
    7. Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis BMC Complementary and Alternative Medicine · 2013
    8. Focus on Skin as a Possible Port of Entry for Solid Nanoparticles and the Toxicological Impact Journal of biomedical nanotechnology · 2010
    9. Follicular and Percutaneous Penetration Pathways of Topically Applied Minoxidil Foam European Journal of Pharmaceutics and Biopharmaceutics · 2010
    10. Transcutol-Containing Vesicles for Topical Delivery of Minoxidil Journal of Drug Targeting · 2010
    11. Formulation and In Vitro Assessment of Minoxidil Niosomes for Enhanced Skin Delivery International Journal of Pharmaceutics · 2009
    12. Determination of the Cuticle Thickness of Human and Porcine Hairs and Their Potential Influence on the Penetration of Nanoparticles into the Hair Follicles Journal of Biomedical Optics · 2009
    13. An Open, Randomized, Comparative Study of Oral Finasteride and 5% Topical Minoxidil in Male Androgenetic Alopecia Dermatology · 2004