Role of Liposomal Drug-Delivery System in Cosmetics

    January 2016 in “ Elsevier eBooks
    Vandana Soni, Silki Chandel, Priyanka Jain, Saket Asati
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    TLDR Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
    The document from 2016 examines the use of liposomal drug-delivery systems in cosmetics, emphasizing their advantages in enhancing the delivery and efficacy of active ingredients for skin and hair care. Liposomes, which are biodegradable and mimic natural membranes, can encapsulate both hydrophilic and lipophilic compounds, offering benefits such as increased stability, hydration, and bioavailability of cosmetic products. They have been incorporated into various products, including anti-aging creams and treatments for acne, psoriasis, and alopecia. For instance, liposomal minoxidil showed improved effectiveness for hair loss, and liposomal dithranol gel was as effective as higher concentration creams for psoriasis with fewer side effects. Despite their benefits, liposomal formulations face challenges such as shorter shelf life and higher costs due to their instability and expensive components. The document also discusses the potential for liposomes to deliver antioxidants, improve skin aging, and provide photoprotection. It concludes that liposomes are promising carriers for topical applications, with a future increase in their use in the cosmetic market anticipated, but also notes the importance of safety testing and proper labeling for nanomaterials in cosmetics.
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