TLDR Liposomes improve the delivery and effectiveness of cosmetic ingredients but face challenges like cost and stability.
The document from 2016 examines the use of liposomal drug-delivery systems in cosmetics, emphasizing their advantages in enhancing the delivery and efficacy of active ingredients for skin and hair care. Liposomes, which are biodegradable and mimic natural membranes, can encapsulate both hydrophilic and lipophilic compounds, offering benefits such as increased stability, hydration, and bioavailability of cosmetic products. They have been incorporated into various products, including anti-aging creams and treatments for acne, psoriasis, and alopecia. For instance, liposomal minoxidil showed improved effectiveness for hair loss, and liposomal dithranol gel was as effective as higher concentration creams for psoriasis with fewer side effects. Despite their benefits, liposomal formulations face challenges such as shorter shelf life and higher costs due to their instability and expensive components. The document also discusses the potential for liposomes to deliver antioxidants, improve skin aging, and provide photoprotection. It concludes that liposomes are promising carriers for topical applications, with a future increase in their use in the cosmetic market anticipated, but also notes the importance of safety testing and proper labeling for nanomaterials in cosmetics.
11 citations,
April 2011 in “Biomolecules & Therapeutics” Anionic liposome formulations of finasteride may effectively treat hair loss with fewer side effects.
24 citations,
November 2009 in “Pharmaceutical Development and Technology” Transcutol P best increases Finasteride absorption for hair loss treatment.
140 citations,
January 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Liposomes improve drug delivery and reduce skin irritation in dermatology.
85 citations,
January 2007 in “Journal of Drug Targeting” Liposomes better deliver minoxidil for hair loss treatment than niosomes.
127 citations,
June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
34 citations,
March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
32 citations,
November 1996 in “International Journal of Dermatology” Antiandrogens can help treat skin conditions like acne and excessive hair in women when used carefully.
232 citations,
June 1975 in “Journal of Steroid Biochemistry” Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
151 citations,
July 2011 in “Archives of Dermatological Research” Liposomal systems show promise for delivering drugs through the skin but face challenges like high costs and stability issues.
111 citations,
March 2012 in “Expert Opinion on Drug Delivery” Liposomes could improve how skin care products work but are costly and not very stable.
127 citations,
June 2006 in “International Journal of Pharmaceutics” Liposomes and niosomes improve finasteride delivery for hair loss treatment.
34 citations,
March 2004 in “Journal of Liposome Research” Minoxidil-loaded liposomes effectively deliver to hair follicles, potentially improving hair growth and treating alopecia.
268 citations,
April 2009 in “International Journal of Pharmaceutics” Niosomes improve minoxidil skin delivery for hair loss treatment.