Integration Analysis of Hair Follicle Transcriptome and Proteome Reveals the Mechanisms Regulating Wool Fiber Diameter in Angora Rabbits

    March 2024 in “ International journal of molecular sciences ”
    Dongwei Huang, Haisheng Ding, Yuanlang Wang … Haizhen Zhao
    Studysummary In this study on Angora rabbits, researchers identified genetic factors influencing wool fiber diameter by analyzing hair follicle proteins, highlighting keratin family members and other proteins as key contributors to fiber differences between coarse and fine wool.
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    Research cited in this study 24

    1. Single-Cell Transcriptome Sequence Profiling on the Morphogenesis of Secondary Hair Follicles in Ordos Fine-Wool Sheep International journal of molecular sciences · 2024
    2. Hair Follicle Development of Rex Rabbits Is Regulated Seasonally by Wnt10b/β-Catenin, TGFβ-BMP, IGF1, and EGF Signaling Pathways Animals · 2023
    3. A Homozygous Missense Mutation in the Fibroblast Growth Factor 5 Gene Is Associated with the Long-Hair Trait in Angora Rabbits BMC genomics · 2023
    4. Hair Follicle Transcriptome Analysis Reveals Genes Regulating Wool Fiber Diameter in Angora Rabbits Biology · 2023
    5. Proteomics-Based Screening of Differentially Expressed Proteins in Skin of Chinese Merino Fine Sheep (JunKen Type) by Gender PubMed · 2022
    6. Identification of the Key Proteins Associated With Different Hair Types in Sheep and Goats Frontiers in genetics · 2022
    7. Promoter Methylation Changes in KRT17: A Novel Epigenetic Marker for Wool Production in Angora Rabbit International journal of molecular sciences · 2022
    8. Integration Analysis of Transcriptome and Proteome Reveals the Mechanisms of Goat Wool Bending Frontiers in cell and developmental biology · 2022
    9. The Fiber Diameter Traits of Tibetan Cashmere Goats Are Governed by the Inherent Differences in Stress, Hypoxic, and Metabolic Adaptations: An Integrative Study of Proteome and Transcriptome BMC Genomics · 2022
    10. Rabbits: Domestication and Molecular Genetics of Hair Coat Development and Quality Animal Genetics · 2020
    11. Discovery of Genes and Proteins Possibly Regulating Mean Wool Fibre Diameter Using cDNA Microarray and Proteomic Approaches Scientific reports · 2020
    12. An Integrated Analysis of Cashmere Fineness lncRNAs in Cashmere Goats Genes · 2019
    13. Comparative Proteomic Analyses Using iTRAQ-Labeling Provides Insights Into Fiber Diversity in Sheep and Goats Journal of proteomics · 2017
    14. Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats Gene · 2015
    15. De Novo Assembly and Characterization of Skin Transcriptome Using RNA Sequencing in Sheep (Ovis Aries) Genetics and Molecular Research · 2015
    16. Signaling Involved in Hair Follicle Morphogenesis and Development International Journal of Molecular Sciences · 2014
    17. Transcriptome Sequencing Reveals Differences Between Primary and Secondary Hair Follicle-Derived Dermal Papilla Cells of the Cashmere Goat PLoS ONE · 2013
    18. Expression Analysis of the Type I Keratin Protein Keratin 33A in Goat Coat Hair Animal science journal · 2011
    19. Fundamental Hair Follicle Biology and Fine Fibre Production in Animals animal · 2010
    20. The Hair Follicle as an Estrogen Target and Source Endocrine Reviews · 2006
    21. Pharmacologic Interventions in Aging Hair Clinical Interventions in Aging · 2006
    22. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor Alpha Is Checked by ER Beta Signaling Endocrinology · 2005
    23. The Role of Keratin Proteins and Their Genes in the Growth, Structure, and Properties of Hair Birkhäuser Basel eBooks · 1997
    24. Growth of Secondary Hair Follicles of the Cashmere Goat In Vitro and Their Response to Prolactin and Melatonin PubMed · 1994

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