Expression Analysis of the Type I Keratin Protein Keratin 33A in Goat Coat Hair

    July 2011 in “ Animal science journal ”
    Yuta Seki, Michinari Yokohama, Kenta Wada, Masatoshi Fujita, Mai Kotani, Yoshio Nagura, Masako Kanno, Kou Nomura, Takashi Amano, Yoshiaki Kikkawa
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    TLDR Keratin 33A is a key protein in goat winter coats, especially in high-producing breeds.
    The study focused on the expression of the keratin 33A protein in goat coat hair, revealing that it is a major keratin highly expressed in winter coats. Western analysis showed that keratin 33A is specific to hair coat tissues and its expression increased in winter for high-producing Korean native breeds but not in low-producing Saanen breeds. Immunohistochemistry localized keratin 33A in the cortex of cashmere fibers, confirming its role as a structural protein in goat cashmere hair.
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