Differential Expression of Type I IRS Keratin Genes in Three Breeds of Sheep

    January 2012 in “ Zhongguo shouyi xuebao
    Jifeng Liu
    TLDR Sheep breeds show different keratin gene expression in the groin, linked to hair follicle density.
    The study examined the expression of type I IRS keratin genes in the neck and groin during the wool growth phase in Aohan fine wool sheep, small-tail Han sheep, and Laiwu black goat. It found no significant differences in the expression of KRT25, KRT26, and KRT27 genes in the neck among the three breeds. However, there were highly significant differences in the groin, with a fold change of 2 and P<0.01. The results from gene expression microarray were consistent with real-time PCR findings. The expression of these genes was related to the hair follicle density in specific body parts of the sheep.
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