Molecular Cloning and Expression Analysis of Prostaglandin E Receptor 2 Gene in Cashmere Goat (Capra hircus) Skin During Hair Follicle Development
February 2014
in “
Animal Biotechnology
”
Studysummary This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
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The study from 2014 investigated the Prostaglandin E Receptor 2 (PTGER2) gene in Cashmere goat skin, cloning its full-length coding sequence of 1047 base pairs and analyzing its expression during hair follicle development. The PTGER2 gene, which encodes for a protein with 348 amino acids and typical G-protein coupled receptor features, was found to be strongly expressed in the skin. Its expression levels decreased from the anagen phase to the catagen phase and were lowest during the telogen phase, indicating a potential link between PTGER2 expression and the hair follicle cycle in Cashmere goats. However, the number of animals used in the study was not provided, which is a critical factor for evaluating the study's robustness.
