Identification of Differentially Expressed GNAS and GNA11 in Sheep (Ovis Aries) Skins Associated with White and Black Coat Colors
January 2016
in “
Acta histochemica
”
Studysummary This study found that Gnαs and Gnα11 proteins were significantly more expressed in the skin of black sheep compared to white sheep, suggesting their role in coat color regulation.
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The study identified that Gnαs and Gnα11 mRNA and protein expression levels were significantly higher in black sheep skin compared to white sheep skin, with Gnα11 showing higher expression than Gnαs in both skin colors. These proteins were located in the outer root sheath and hair papilla of hair follicles. The findings suggested that Gnαs and Gnα11 might play a role in the formation of coat hair color in sheep. The study involved six one-year-old female sheep, three with white coats and three with black coats.
