Role of Direct Immunofluorescence on Outer Root Sheath of Hair Follicle in Monitoring Disease Activity of Pemphigus Vulgaris

September 2017 in “ Journal of Pathology of Nepal ”

Mst. Sayedatun Nessa, Nurul Akmn Kabir, Ashim Ranjan Barua, Harasit Kumar Paul

direct immunofluorescence outer root sheath hair follicle pemphigus vulgaris skin biopsy scalp hair samples immune system skin mucous membranes DIF hair root sheath hair

TLDR Testing hair roots with a special dye is a simple, non-invasive way to check disease progress in pemphigus vulgaris patients.

The study investigated the effectiveness of using direct immunofluorescence on the outer root sheath of hair follicles to monitor disease activity in patients with pemphigus vulgaris, a condition where the immune system attacks the skin and mucous membranes. The study included 16 patients who had been in clinical remission for at least three months. Both skin biopsy samples and plucked scalp hair samples were stained and analyzed. The results showed that direct immunofluorescence was positive in 13 out of 16 patients (81.25%) for both hair and skin samples. The conclusion drawn from the study was that direct immunofluorescence of hair is a simple, specific, and non-invasive method that can potentially replace repeated skin biopsies for monitoring disease activity in pemphigus vulgaris patients.

View this study on nepjol.info →

Discuss this study in the Community →

Related Community Posts Join

6 / 338 results

community Anyone else buy their Ru58841 direct from a chinese supplier?

in Treatment 1 upvotes 2 months ago

The conversation discusses buying RU58841 directly from a Chinese supplier for cost savings. It mentions that companies like Anageninc and Actifolic do the same.

community Just took a pic of my hair under direct sunlight for the first time in months. Instant regret.

in Chat 20 upvotes 3 years ago

The conversation is about disappointment with hair loss progress despite using treatments like finasteride, minoxidil, nizoral, tretinoin, and a dermaroller. Direct sunlight revealed more hair loss than expected, prompting continued treatment and hope for improvement.

community Any Recommendations For Exosome Treatments In The Greater Sacramento Area?

in Treatment 2 upvotes 4 months ago

A user is seeking recommendations for dermatologists or hair clinics in the Greater Sacramento or Bay Area for exosome treatments, comparing topical application plus microneedling versus direct scalp injections. They are also asking for personal experiences and before-and-after photos.

community 12 months using Ru, dutasteride, minoxidil

in Progress Pictures 27 upvotes 1 year ago

A user's 12-month progress using RU58841, dutasteride, and minoxidil for hair loss. The user is open to answering questions via direct message.

community Spironolactone or bicalutamide prescription

in Treatment 4 upvotes 1 year ago

The conversation is about someone seeking a doctor in the EU who prescribes spironolactone or bicalutamide for female pattern hair loss, as they are having difficulty finding treatment options beyond Minoxidil in Austria. They are asking for recommendations and are open to direct messages for assistance.

community HMI-115 – Anyone have the old Moeman32 posts saved?

in Research/Science 27 upvotes 1 year ago

Treatments for hair loss, specifically the use of minoxidil, finasteride and RU58841. Replies to this post suggest that users should share relevant information publicly rather than through direct messages.

Related Research

1 / 1 results

research Role of Direct Immunofluorescence on Outer Root Sheath of Hair Follicle in Monitoring Disease Activity of Pemphigus Vulgaris

1 citations, September 2017 in “Journal of Pathology of Nepal”

Testing hair roots with a special dye is a simple, non-invasive way to check disease progress in pemphigus vulgaris patients.