Search

for
Search:

Research

5 / 1000+ results

research Regulation of hair follicle development by exosomes derived from dermal papilla cells

87 citations , April 2018 in “Biochemical and Biophysical Research Communications”

In this study, dermal papilla cell-derived exosomes accelerated hair follicle growth in mice, suggesting potential for treating hair loss by modulating key signaling pathways.

research Simple and rapid method to isolate and culture follicular papillae from human scalp hair follicles

78 citations , August 2002 in “Experimental Dermatology”

This study describes a simplified method for isolating and cultivating human hair follicle papillae that can be easily executed by new lab personnel.

research Exosomal Micro RNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation

71 citations , January 2019 in “International journal of biological sciences”

This study proposes the miR-22-5p-LEF1 axis as a novel pathway that may regulate hair follicle stem cell proliferation.

Effects of Epidermal Growth Factor, Fibroblast Growth Factor, Minoxidil, and Hydrocortisone on Growth Kinetics in Human Hair Bulb Papilla Cells and Root Sheath Fibroblasts Cultured In Vitro

research Effects of epidermal growth factor, fibroblast growth factor, minoxidil and hydrocortisone on growth kinetics in human hair bulb papilla cells and root sheath fibroblasts cultured in vitro

58 citations , June 1987 in “Archives of Dermatological Research”

This study found that epidermal and fibroblast growth factors increased proliferation of human hair bulb papilla cells and root sheath fibroblasts in vitro, while hydrocortisone decreased it and minoxidil had no effect.

Role of Hair Papilla Cells in Induction and Regeneration Processes of Hair Follicles

research Role of hair papilla cells on induction and regeneration processes of hair follicles

57 citations , November 1998 in “Wound Repair and Regeneration”

This research observed that dermal papilla cells have the potential to regenerate hair bulbs under preferred environmental conditions when associated with dermal sheath cells or exposed to specific growth factors.

View more "hair papilla" in research →

Community Join

5 / 1000+ results

community Hair follicle dermal papilla exosomes

2 upvotes 1 year ago

The conversation discusses using hair follicle dermal papilla exosomes for hair loss treatment. It inquires about purchasing options for this treatment.

community HairClone (UK) finally begins offering its Dermal Papilla Cell Hair Multiplication procedure to humans. In Guatemala.

149 upvotes 6 months ago

HairClone is offering a Dermal Papilla Cell Hair Multiplication procedure in Guatemala, raising questions about its effectiveness and regulatory reasons for the location. Users express skepticism and curiosity about the treatment's success and potential costs.

community New Peer-Reviewed Publication Further Validates RepliCel's Use of Dermal Sheath Cup Cells to Treat Pattern Baldness - Paper entitled "Hair Follicle Dermal Stem Cells Regenerate the Dermal Sheath, Repopulate the Dermal Papilla, and Modulate Hair Type" published journal Developmental Cell

13 upvotes 11 years ago

A new treatment using dermal sheath cup cells may regrow hair and could require repeat treatments every 8 years. Users discuss ongoing trials and plan to use finasteride and minoxidil until the treatment is available.

community New Hair Loss Cure: AMP-303 Is Back. It’s what PP405 should have been.

7 upvotes 5 months ago

AMP-303 and AMP-601 are new hair loss treatments targeting dermal papilla cells, with AMP-303 showing early efficacy in transitioning vellus hairs to terminal hairs after one injection. Further clinical trials are planned, and these treatments are seen as promising due to their biologic approach and less frequent application compared to daily treatments.

community [Nov 2019] The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

23 upvotes 6 years ago

A peptide from Japanese water chestnut fruit may help with hair loss by suppressing DHT's effect on hair follicle cell death, potentially serving as a finasteride alternative. The treatment's effectiveness and safety in humans remain uncertain.

View more "hair papilla" in community →

Clinics

6 / 180 results

All 180 clinic results →

Learn

8 / 66 results

learn SCUBE3

a signaling molecule from dermal papilla cells being actively researched

How does SCUBE3 work on hair follicles compared to treatments like minoxidil or finasteride? Laboratory research in mice reports that SCUBE3, a protein released by dermal papilla cells, signals dormant follicles to grow through the TGF-β pathway downstream of Hedgehog; minoxidil and finasteride instead work on blood flow to the follicle and on DHT, and unlike SCUBE3 they have decades of human trial data behind them. SCUBE3 has not been tested in human clinical trials and is not available as a medicine.

learn Centella

Not eating well lately and your hair’s falling? A centella-based supplement might give your roots the boost they’re begging for. There is no published human trial showing that an oral Centella asiatica (gotu kola) supplement stops hair shedding caused by poor nutrition; the evidence is laboratory work on dermal papilla cells, inflammation and collagen, and community reports mention centella only in topical products.

learn Platelet-Rich Plasma

What is Platelet-Derived Growth Factor Beta Polypeptide, and how does it help stimulate new hair growth? PDGF-BB is a growth factor that signals to dermal papilla cells and promotes blood-vessel formation; mouse studies report it can push follicles into the growth phase, and human evidence comes only indirectly from PRP trials. No PDGF product is approved for hair restoration and there is no published human trial of PDGF-BB on its own.

learn Hair Multiplication

extract, clone, and reinsert your own hair cells

learn Valproic acid

an anticonvulsant repurposed for hair loss via histone inhibition

learn Dexpanthenol

precursor of vitamin B5 with hair stimulating effects

learn Exosomes

Microscopic delivery system that sends growth-promoting signals to hair follicles

learn Hair Fibers

Do hair fibers really make thinning hair look fuller, or is it just an illusion? Hair fibers create an optical illusion of fullness but do not actually thicken hair.
How do you apply hair fibers correctly so they stay in place all day? Apply hair fibers to clean, dry hair and use a setting spray for better hold.

View more "hair papilla" in learn →

Experts

1 / 5 results

Unscored
SMP Specialist
Hairo Fallas
Newark, NJ, United States

Hairo Fallas