Identification of Differentially Expressed Genes During a Wool Follicle Growth Cycle Induced by Prolactin

December 1999 in “ Journal of Investigative Dermatology ”

Nicholas Rufaut, A.J. Pearson, A. J. Nixon, Thomas T. Wheeler, Richard J. Wilkins

prolactin wool follicle KRTAP3.2 desmoglein 1 stratifin Clk3 telogen phase anagen phase follicle structure cell cycling differentiation RNA splicing

Studysummary This study found that manipulating prolactin levels in New Zealand Wiltshire sheep induces wool follicle growth cycles, revealing gene expression changes that suggest roles for specific genes in follicle function.

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