Evaluation of Effectiveness of I-PRF Mesotherapy and I-PRF Mesotherapy with Microneedling in Treatment of Male Androgenetic Alopecia: A Comparative Study

    August 2026 in “ Journal of Maxillofacial and Oral Surgery ”
    PRATIKSHA SHETTY -, Piyash Basu, Padmaraj Hegde
    Studysummary This study investigated treatments for male androgenetic alopecia, finding that combining injectable platelet-rich fibrin (i-PRF) with microneedling increased hair growth more effectively than i-PRF alone according to questionnaires and photographic assessments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 28

    1. Injectable Platelet-Rich Fibrin Promotes Proliferation and Trichogenic Inductivity of Dermal Papilla Cells Through Activating TGF-β/Smad Signaling Pathway Cellular and Molecular Biology · 2024
    2. Androgenetic Alopecia: An Update JAAD International · 2023
    3. Platelet Rich Plasma Combination Therapies for Treatment of Androgenetic Alopecia: A Systematic Review Journal of Cutaneous and Aesthetic Surgery · 2023
    4. Integrative and Mechanistic Approach to the Hair Growth Cycle and Hair Loss Journal of Clinical Medicine · 2023
    5. Injectable Platelet Rich Fibrin Therapy for Androgenetic Alopecia: A Series of 15 Cases International Journal of Research in Dermatology · 2022
    6. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    7. Combination Therapy with Injectable Platelet-Rich Fibrin and Microneedling for Male Androgenetic Alopecia: An Evaluation of Current Practice Journal of Aesthetic Nursing · 2021
    8. Injectable Platelet Rich Fibrin Facilitates Hair Follicle Regeneration by Promoting Human Dermal Papilla Cell Proliferation, Migration, and Trichogenic Inductivity Experimental Cell Research · 2021
    9. Comparative Study of Efficacy of Minoxidil Versus Minoxidil with Platelet-Rich Plasma Versus Minoxidil with Dermaroller in Androgenetic Alopecia International Journal of Research in Dermatology · 2021
    10. Androgenetic Alopecia in Women and Men: Italian Guidelines Adapted from European Dermatology Forum/European Academy of Dermatology and Venereology Guidelines Giornale italiano di dermatologia e venereologia · 2020
    11. Efficacy and Safety of Oral Minoxidil 5 mg Once Daily in the Treatment of Male Patients with Androgenetic Alopecia: An Open-Label and Global Photographic Assessment Dermatology and therapy · 2020
    12. Usefulness of Home-Use Microneedle Devices in the Treatment of Pattern Hair Loss Journal of cosmetic dermatology · 2020
    13. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    14. Platelet-Rich Plasma and Microneedling Improve Hair Growth in Patients with Androgenetic Alopecia When Used as an Adjuvant to Minoxidil Journal of Cosmetic Dermatology · 2019
    15. A Study to Compare the Efficacy of Platelet-Rich Plasma and Minoxidil Therapy for the Treatment of Androgenetic Alopecia International Journal of Trichology · 2019
    16. Long-Term (10-Year) Efficacy of Finasteride in 523 Japanese Men with Androgenetic Alopecia Clinical research and trials · 2019
    17. A Pilot Split-Scalp Study of Combined Fractional Radiofrequency Microneedling and 5% Topical Minoxidil in Treating Male Pattern Hair Loss Clinical and Experimental Dermatology · 2018
    18. A Randomized Controlled, Single-Observer Blinded Study to Determine the Efficacy of Topical Minoxidil Plus Microneedling Versus Topical Minoxidil Alone in the Treatment of Androgenetic Alopecia Journal of Cutaneous and Aesthetic Surgery · 2018
    19. Randomized Trial of Electrodynamic Microneedle Combined with 5% Minoxidil Topical Solution for the Treatment of Chinese Male Androgenetic Alopecia Journal of Cosmetic and Laser Therapy · 2017
    20. Randomized Placebo-Controlled, Double-Blind, Half-Head Study to Assess the Efficacy of Platelet-Rich Plasma on the Treatment of Androgenetic Alopecia Dermatologic Surgery · 2016
    21. Platelet-Rich Plasma Microneedling Versus 5% Topical Minoxidil in the Treatment of Patterned Hair Loss Journal of the Egyptian Women's Dermatologic Society (Print) · 2016
    22. A Randomized Evaluator Blinded Study of Effect of Microneedling in Androgenetic Alopecia: A Pilot Study International Journal of Trichology · 2013
    23. Male Androgenetic Alopecia: Population-Based Study in 1,005 Subjects International Journal of Trichology · 2009
    24. The Hair Cycle Journal of Cell Science · 2006
    25. Use of Finasteride in the Treatment of Men With Androgenetic Alopecia Journal of Investigative Dermatology Symposium Proceedings · 2003
    26. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    27. The Biology of Hair Follicles The New England Journal of Medicine · 1999
    28. A Hair Growth Questionnaire for Use in the Evaluation of Therapeutic Effects in Men Journal of Dermatological Treatment · 1998