Comparison of Efficacy of Various Modalities of Treatment in Patients with Androgenetic Alopecia

In a randomized clinical trial conducted from February 2018 to January 2019, 80 male patients with androgenetic alopecia were treated with either topical 5% minoxidil along with minoxidil mesotherapy or platelet-rich plasma (PRP) microneedling. The study found no significant improvement in either group after 3 months of treatment. However, after 6 months, the group treated with 5% minoxidil showed a significantly better response than the PRP microneedling group. The study concluded that PRP microneedling treatment once a month was not as effective as daily application of 5% minoxidil with once a month 5% minoxidil mesotherapy. The study suggested that PRP, if used as a single treatment modality, would not be effective and should be combined with either topical minoxidil or oral finasteride.