The Significance of CYP11A1 Expression in Skin Physiology and Pathology
March 2021
in “
Molecular and Cellular Endocrinology
”
Research cited in this study
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Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.
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Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
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Stress can worsen skin conditions and stop hair growth by affecting the body's stress response system.
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Human hair follicles can produce cortisol like the body's stress response system.
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Human skin can make serotonin and melatonin, which help protect and maintain it.
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Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
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Human skin can produce steroids from cholesterol.
research Androgen Receptor-Mediated Inhibition of Cutaneous Wound Healing
Blocking testosterone speeds up wound healing in males.
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CRH promotes fat production in skin cells, affecting conditions like acne.
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