21 citations
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May 2022 in “Frontiers in Cell and Developmental Biology” Hair growth and health are influenced by factors like age, environment, and nutrition, and are controlled by various molecular pathways. Red light can promote hair growth, and understanding these processes can help treat hair-related diseases.
April 2016 in “Journal of Investigative Dermatology” Wnt ligands, produced by dermal papilla cells, are essential for adult hair growth and regeneration.
8 citations
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January 2016 in “Journal of Investigative Dermatology” The research created a model to understand human hair growth cycle, which can help diagnose and treat hair growth disorders and test potential hair growth drugs.
1 citations
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December 2012 in “Journal of Dermatological Science” 158 citations
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February 2012 in “Journal of Investigative Dermatology” 10 citations
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October 2000 in “PubMed” The study investigated the effects of expressing human papillomavirus type 16 E6/E7 oncogenes in the outer root sheath of hair follicles in transgenic mice. These mice exhibited a fur phenotype with lower hair density but faster hair regeneration compared to wild-type mice. The expression of these oncogenes extended the growth phase (anagen) of hair follicles and bypassed the resting phase (telogen), leading to continuous hair follicle cycling. Although the first hair growth cycle appeared normal, the second cycle showed delayed initiation of catagen and insensitivity to telogen resting signals, even with estradiol present. This indicated that E6/E7 expression in the ORS delayed catagen entry and prevented telogen rest, resulting in ongoing hair follicle cycling.