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research Skin steroidogenesis in health and disease

47 citations , September 2016 in “Reviews in endocrine and metabolic disorders”

This review discusses the steroidogenic properties of human skin and suggests that impaired steroidogenesis may be linked to conditions like acne, rosacea, atopic dermatitis, and androgenic alopecia, but reports no new clinical results.

research Local synthesis and effect of sex steroids in human skin and the hair follicle and hormonal effects on the wound healing response

January 2011 in “Padua Research Archive (University of Padua)”

This study suggests that human skin locally synthesizes active sex steroid hormones, impacting inflammation, cell behavior, and wound healing, with potential implications for therapies in aging and impaired wound recovery.

Effects of Sex Steroid Deprivation and Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

research Effects of Sex Steroid Deprivation/Administration on Hair Growth and Skin Sebum Production in Transsexual Males and Females

176 citations , August 2000 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism”

In this study, cross-sex hormone therapy affected hair growth patterns differently, with estrogen reducing hair growth in male-to-female transsexuals and testosterone increasing it in female-to-male transsexuals; however, male typical hair diameters were not fully reached in the latter group after 12 months.

Sex Steroid Hormone Receptors in Human Skin Appendages and Their Neoplasms

research Sex Steroid Hormone Receptors in Human Skin Appendage and its Neoplasms

59 citations , January 2005 in “Endocrine Journal”

This study found that sex steroid hormone receptors are largely maintained during the transformation of skin appendages to neoplasms, except for androgen and estrogen receptors in sweat and sebaceous gland tumors.

research Drug utilization of topical and systemic steroids in treating various skin diseases in the dermatology department of a teaching hospital, Bangalore

January 2023 in “International Journal of Pharmacy and Pharmaceutical Science”

In this observational study conducted in Bengaluru, India, among 272 dermatology patients, the authors reported that dermatitis was the most common condition treated with corticosteroids, with a preference for topical applications; desonide was the most frequently prescribed drug.

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Community Join

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community Can I use topical steroid along finasteride to reduce scalp inflammation and hairloss?

6 upvotes 7 years ago

The user asks if finasteride can be used with the topical steroid betamethasone dipropionate to reduce hair loss and scalp inflammation. The discussion revolves around combining these treatments for better results.

community I always hear the advice to reduce scalp inflammation. What are some non-steroidal ways to reduce inflammation?

in Treatment 13 upvotes 1 year ago

Non-steroidal ways to reduce scalp inflammation include using topical melatonin, urea shampoo, Zyrtec, turmeric with black pepper, omega-3 supplements, a self-made topical solution with cetirizine, melatonin, and piroctone olamine, ketoconazole shampoo, witch hazel shampoo, tacrolimus, and lifestyle changes like a healthy diet and regular exercise. Some users also mentioned unconventional methods like infrared light therapy and a carnivore diet.

community Dutasteride vs Finasteride and Steroid

in Progress Pictures 87 upvotes 11 months ago

Dutasteride is preferred over finasteride for hair loss due to fewer side effects. Combining dutasteride with minoxidil and RU58841 is effective for hair regrowth, even during steroid use.

community My hair after 3 steroid cycles

in Progress Pictures 27 upvotes 2 years ago

A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.

community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.

12 upvotes 2 years ago

The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.

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Learn

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learn Hydrocortisone

a synthetic cortisol used for anti-inflammatory effects

Can hydrocortisone be used together with other treatments like minoxidil or steroid injections? Clinicians do use a mild steroid cream to settle the scalp irritation minoxidil can cause, but no verified trial tests hydrocortisone added to minoxidil or to corticosteroid injections, and prolonged scalp use risks skin thinning — combining it is a decision to take with a prescriber.
Is hydrocortisone effective for stopping inflammation that blocks hair growth? Sources describe hydrocortisone as a short-course treatment for scalp inflammation such as seborrhoeic dermatitis or eczema, and no verified trial tests it as a hair-regrowth treatment; the corticosteroids used for alopecia areata are the potent prescription ones, and prolonged use of any topical steroid on the scalp risks skin thinning.

learn Fluocinolone

Can long-term use of Fluocinolone affect the health of hair follicles? There is no long-term human trial measuring what topical fluocinolone does to hair follicles; what is documented is the label's warning about skin atrophy with prolonged use, plus a 2007 mouse study suggesting hair-follicle bulge stem cells do not repair steroid-induced atrophy.