Cedrol in Ginger (Zingiber Officinale) as a Promising Hair Growth Drug: The Effects of Oral and External Administration on Hair Regeneration and Its Mechanism
August 2024
in “
Bioorganic Chemistry
”
Cedrol ginger Zingiber officinale hair regeneration cyclophosphamide-induced alopecia areata oral administration external application hair growth follicle damage cell proliferation JAK3/STAT3 signaling pathway Wnt3α/β-catenin germinal center oxidative stress hair loss alopecia areata oral treatment topical treatment hair follicles cell growth JAK3/STAT3 pathway Wnt pathway
Studysummary This study found that oral administration of cedrol, a component of ginger, improved hair regeneration and reduced hair follicle damage in cyclophosphamide-induced alopecia areata in mice more effectively than external administration, by enhancing cytokine expression and modulating key signaling pathways.
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