Plant Nanovesicles Integrate Bioactivity and Transdermal Finasteride Delivery for Androgenetic Alopecia

    November 2025 in “ ACS Applied Materials & Interfaces ”
    Fan Qi, Huijun Xie, Xun Guo … Yuan Zhang
    Studysummary This study found that in a mouse model of androgenetic alopecia, topical application of finasteride-loaded Platycladi cacumen-derived nanovesicles improved hair regrowth more effectively than minoxidil.
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    Research cited in this study 31

    1. Microenvironment-Responsive Recombinant Collagen XVII-Based Composite Microneedles for the Treatment of Androgenetic Alopecia Acta Biomaterialia · 2025
    2. Recent Advances in Drug Development for Hair Loss International Journal of Molecular Sciences · 2025
    3. Deoxyshikonin From Arnebiae Radix Promotes Hair Growth By Targeting The Wnt/β-Catenin Signaling Pathway Phytomedicine · 2025
    4. Nanoparticle Adjuvants Incorporating Haptens Drive Potent Immune Tolerance to Accelerate Hair Regrowth ACS Applied Materials & Interfaces · 2025
    5. Dahuang-Gancao Decoction Ameliorates Testosterone-Induced Androgenetic Alopecia in Mice Journal of Ethnopharmacology · 2025
    6. Robust Metformin Nanosystem Promotes Hair Growth In Androgenetic Alopecia Research · 2025
    7. Antioxidant Properties of Platycladus Orientalis Flavonoids for Treating UV-Induced Damage in Androgenetic Alopecia Hair Molecules/Molecules online/Molecules annual · 2024
    8. Polydopamine Synergizes with Quercetin Nanosystem to Reshape the Perifollicular Microenvironment for Accelerating Hair Regrowth in Androgenetic Alopecia Nano letters · 2024
    9. Efficacy and Safety of Combined Microneedling Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis of Randomized Clinical Trials Journal of Cosmetic Dermatology · 2024
    10. Development and Evaluation of Finasteride Niosomes Targeting Hair Follicles for Androgenic Alopecia Management Journal of Drug Delivery Science and Technology · 2023
    11. Androgenetic Alopecia: Therapy Update Drugs · 2023
    12. Water Extract of Cacumen Platycladi Promotes Hair Growth Through the Akt/GSK3β/β-Catenin Signaling Pathway Frontiers in Pharmacology · 2023
    13. A Multifunctional Cholesterol-Free Liposomal Platform Based on Protopanaxadiol for Alopecia Therapy Nano Research · 2022
    14. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
    15. Treatment Options for Androgenetic Alopecia: Efficacy, Side Effects, Compliance, Financial Considerations, and Ethics Journal of Cosmetic Dermatology · 2021
    16. Finasteride for Hair Loss: A Review Journal of Dermatological Treatment · 2021
    17. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021
    18. Topical Finasteride for the Treatment of Male Androgenetic Alopecia and Female Pattern Hair Loss: A Review of the Current Literature Journal of Dermatological Treatment · 2020
    19. Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy International Journal of Molecular Sciences · 2020
    20. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    21. Minoxidil And Its Use In Hair Disorders: A Review Drug Design Development and Therapy · 2019
    22. Advances in Regenerative Stem Cell Therapy in Androgenic Alopecia and Hair Loss: Wnt Pathway, Growth Factor, and Mesenchymal Stem Cell Signaling Impact Analysis on Cell Growth and Hair Follicle Development Cells · 2019
    23. In Vivo and In Vitro Evaluation of Hair Growth Potential of Cacumen Platycladi, and GC-MS Analysis of the Active Constituents of Volatile Oil Journal of ethnopharmacology · 2019
    24. Activating Wnt/β-Catenin Signaling Pathway for Disease Therapy: Challenges and Opportunities Pharmacology & Therapeutics · 2018
    25. Proprietary Herbal Extract Downregulates the Gene Expression of IL-1α in HaCaT Cells: Possible Implications Against Nonscarring Alopecia Medicinski arhiv · 2018
    26. Topically Used Herbal Products for the Treatment of Hair Loss: Preclinical and Clinical Studies Archives of Dermatological Research · 2017
    27. Androgenetic Alopecia: A Review Endocrine · 2017
    28. Hair Growth Promoting Activity of Cedrol Isolated from the Leaves of Platycladus Orientalis Biomedicine & Pharmacotherapy · 2016
    29. Inhibitory Activities of Some Traditional Chinese Herbs Against Testosterone 5α-Reductase and Effects of Cacumen Platycladi on Hair Regrowth in Testosterone-Treated Mice Journal of Ethnopharmacology · 2015
    30. Androgenetic Alopecia: New Insights Into the Pathogenesis and Mechanism of Hair Loss F1000Research · 2015
    31. Hair Growth-Promoting Activity of Hot Water Extract of Thuja Orientalis BMC Complementary and Alternative Medicine · 2013