Interfollicular Epidermal Stem-Like Cells for the Recreation of the Hair Follicle Epithelial Compartment

    January 2021 in “ Stem cell research & therapy ”
    Carla M. Abreu, Rogério P. Pirraco, Rui L. Reis … A. P. Marques
    Studysummary This study suggests that interfollicular epidermal keratinocytes with stem-like features may serve as an alternative to follicular keratinocytes for hair regeneration by supporting hair follicle morphogenesis in vivo.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 33

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    7. Dermal Papilla Cells Improve Wound Healing and Generate Hair Bud-Like Structures in Grafted Skin Substitutes Using Hair Follicle Stem Cells Stem Cells Translational Medicine · 2014
    8. Boosting and Rescuing Epidermal Superior Population from Fresh Keratinocyte Cultures Stem Cells and Development · 2013
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    10. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
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    20. Characterization and Isolation of Stem Cell-Enriched Human Hair Follicle Bulge Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
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    25. Noggin Is Required for Induction of the Hair Follicle Growth Phase in Postnatal Skin The FASEB Journal · 2001
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    27. Inhibition of BMP Signaling Affects Growth and Differentiation in the Anagen Hair Follicle The EMBO Journal · 2000
    28. Expression of Vascular Endothelial Growth Factor (VEGF) in Various Compartments of the Human Hair Follicle Archives of Dermatological Research · 1998
    29. Keratin 19 as a Biochemical Marker of Skin Stem Cells In Vivo and In Vitro: Localization and Variation with Age and Culture Stage Journal of Cell Science · 1996
    30. Loss of Vascular Endothelial Growth Factor in Human Alopecia Hair Follicles Journal of Investigative Dermatology · 1995
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    32. Outer Root Sheath Cells Organize Into Epidermoid Cyst-Like Spheroids When Cultured Inside Matrigel: A Light-Microscopic and Immunohistological Comparison Between Human ORS Cells and Interfollicular Keratinocytes Cell and Tissue Research · 1994
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    Related research 6

    1. Morphogenesis, Growth Cycle, and Molecular Regulation of Hair Follicles Frontiers in Cell and Developmental Biology · 2022
    2. Dermal Papilla-Derived Wnt Ligands Are Required for Adult Hair Follicle Growth Journal of Investigative Dermatology · 2016
    3. Putting the Human Hair Follicle Cycle on the Map Journal of Investigative Dermatology · 2016
    4. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    5. Biology of the Hair Follicle: The Basics Seminars in Cutaneous Medicine and Surgery · 2006
    6. Expression of E6 and E7 Papillomavirus Oncogenes in the Outer Root Sheath of Hair Follicles Extends the Growth Phase and Bypasses Resting at Telogen PubMed · 2000