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research Hypoxia Improves Hair Inductivity of Dermal Papilla Cells via Nuclear NADPH Oxidase 4-Mediated Reactive Oxygen Species Generation

25 citations, January 2019 in “British Journal of Dermatology”

Low oxygen levels can make hair-growing cells better at growing hair through a process involving reactive oxygen species.

research Activating Beta-Catenin Signaling in CD133-Positive Dermal Papilla Cells Increases Hair Inductivity

23 citations, June 2016 in “FEBS Journal”

Boosting β-catenin signaling in certain skin cells can enhance hair growth.

research Effects of the PI3K/Akt Signaling Pathway on the Hair Inductivity of Human Dermal Papilla Cells in Hair Beads

12 citations, April 2022 in “Journal of Bioscience and Bioengineering”

Activating the PI3K/Akt pathway improves hair growth by human dermal papilla cells in hair beads.

research Human Hair Outer Root Sheath Cells and Platelet-Lysis Exosomes Promote Hair Inductivity of Dermal Papilla Cells

9 citations, June 2020 in “Tissue Engineering and Regenerative Medicine”

HHORSC exosomes and PL improve hair growth treatment outcomes.

research Injectable Platelet Rich Fibrin Facilitates Hair Follicle Regeneration by Promoting Human Dermal Papilla Cell Proliferation, Migration, and Trichogenic Inductivity

2 citations, October 2021 in “Experimental Cell Research”

Injectable platelet-rich fibrin helps hair growth by boosting key cell functions.

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community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 5 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community HairClone developing cell replacement treatments for Hair Loss

6 upvotes 6 years ago

HairClone is developing cell replacement treatments to rejuvenate and generate hair follicles, and has launched a crowdfunding campaign. A user expressed skepticism about the need for crowdfunding.

community What to look Forward to in 2025

in Research/Science 20 upvotes 2 months ago

Hair loss treatments are advancing, with Coegin Pharma's FOL005 expected this year and Breezula potentially later. Pyrilutamide is available but not very effective, while Kintor's products face skepticism; traditional treatments like finasteride and minoxidil remain dominant.

community Dont fucking wait to start finasteride!

in Chat 372 upvotes 3 years ago

User baldwarrior85 regrets not starting finasteride earlier to prevent hair loss. Others share their experiences, with some having side effects and others seeing positive results from the treatment.

community How true is the statement: dead follicles don't grow back?

in Research/Science 107 upvotes 4 weeks ago

Hair follicles usually go dormant rather than die, and treatments like finasteride, minoxidil, and hormone therapy can sometimes reactivate them, though results vary. Complete regrowth is rare, especially in long-term bald areas, but some individuals see significant improvement with these treatments.

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