Lymphatic Vessels Interact Dynamically with the Hair Follicle Stem Cell Niche During Skin Regeneration In Vivo

    September 2019 in “ The EMBO Journal ”
    Daniel Peña-Jiménez, Sílvia Fontenete, Diego Megı́as … Mirna Pérez-Moreno
    Studysummary This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
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    Research cited in this study 29

    1. The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms Journal of Dermatological Science · 2018
    2. The Epithelial Stem Cell Niche in Skin Elsevier eBooks · 2017
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    4. Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations Current opinion in genetics & development · 2016
    5. Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma Nature medicine · 2015
    6. Organ-Level Quorum Sensing Directs Regeneration in Hair Stem Cell Populations Cell · 2015
    7. Macrophages Contribute to the Cyclic Activation of Adult Hair Follicle Stem Cells PLoS Biology · 2014
    8. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
    9. Modulating the Stem Cell Niche for Tissue Regeneration Nature Biotechnology · 2014
    10. Macroenvironmental Regulation of Hair Cycling and Collective Regenerative Behavior Cold Spring Harbor Perspectives in Medicine · 2014
    11. Perivascular Hair Follicle Stem Cells Associate With a Venule Annulus Journal of Investigative Dermatology · 2013
    12. Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
    13. Hairy Tale of Signaling in Hair Follicle Development and Cycling Seminars in cell & developmental biology · 2012
    14. Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration Journal of Investigative Dermatology · 2012
    15. Live Imaging of Stem Cell and Progeny Behavior in Physiological Hair-Follicle Regeneration Nature · 2012
    16. Stress-Induced Production of Chemokines by Hair Follicles Regulates the Trafficking of Dendritic Cells in Skin Nature Immunology · 2012
    17. The Functional Organization of Cutaneous Low-Threshold Mechanosensory Neurons Cell · 2011
    18. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011
    19. Nerve-Derived Sonic Hedgehog Defines a Niche for Hair Follicle Stem Cells Capable of Becoming Epidermal Stem Cells Cell stem cell · 2011
    20. Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
    21. The Basement Membrane Of Hair Follicle Stem Cells Is A Muscle Cell Niche Cell · 2011
    22. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    23. Lrig1 Expression Defines a Distinct Multipotent Stem Cell Population in Mammalian Epidermis Cell stem cell · 2009
    24. Epidermal Homeostasis: A Balancing Act of Stem Cells in the Skin Nature Reviews Molecular Cell Biology · 2009
    25. Nfatc1 Balances Quiescence and Proliferation of Skin Stem Cells Cell · 2008
    26. Defining the Impact of Beta-Catenin/Tcf Transactivation on Epithelial Stem Cells Genes & development · 2005
    27. Cyclosporin A-Induced Hair Growth in Mice Is Associated with Inhibition of Calcineurin-Dependent Activation of NFAT in Follicular Keratinocytes American Journal of Physiology-cell Physiology · 2003
    28. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    29. Control of Hair Growth and Follicle Size by VEGF-Mediated Angiogenesis Journal of Clinical Investigation · 2001

    Related research 5

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    2. Expression of Matrix Metalloproteinases and Tissue Inhibitor of Matrix Metalloproteinases in the Hair Cycle Experimental and Therapeutic Medicine · 2016
    3. Hair Cycle Resting Phase Is Regulated by Cyclic Epithelial FGF18 Signaling Journal of Investigative Dermatology · 2012
    4. Hair Follicle Expression of 1,25-Dihydroxyvitamin D3 Receptors During the Murine Hair Cycle British Journal of Dermatology · 2006
    5. Expression of the Bcl-2 Proto-Oncogene in the Cycling Adult Mouse Hair Follicle Journal of Investigative Dermatology · 1994