Studysummary This mathematical model of alopecia areata illustrates how inflammatory autoimmune responses interrupt the anagen phase of hair growth, and may help evaluate treatments and identify new therapeutic targets.
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Research cited in this study 44
- Quorum Sensing and Other Collective Regenerative Behaviors in Organ Populations Current opinion in genetics & development · 2016
- A Novel Therapeutic Paradigm for Patients with Extensive Alopecia Areata Expert Opinion on Biological Therapy · 2016
- Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers Experimental Dermatology · 2016
- A Primer for Studying Cell Cycle Dynamics of the Human Hair Follicle Experimental Dermatology · 2016
- Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse British journal of dermatology/British journal of dermatology, Supplement · 2016
- Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies Autoimmunity reviews · 2016
- Epithelial Skin Biology: Stem Cells and Epidermal Homeostasis Current Topics in Developmental Biology · 2016
- A Guide to Studying Human Hair Follicle Cycling In Vivo Journal of Investigative Dermatology · 2015
- The Role of Lymphocytes in the Development and Treatment of Alopecia Areata Expert Review of Clinical Immunology · 2015
- Treatment Options for Alopecia Expert Opinion on Pharmacotherapy · 2015
- Human Hair Follicle Organ Culture: Theory, Application, and Perspectives Experimental Dermatology · 2015
- An Integrated Transcriptome Atlas of Embryonic Hair Follicle Progenitors, Their Niche, and the Developing Skin Developmental cell · 2015
- Mathematical Model for Alopecia Areata Journal of theoretical biology · 2015
- Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib EBioMedicine · 2015
- Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
- The Peripheral Clock Regulates Human Pigmentation The journal of investigative dermatology/Journal of investigative dermatology · 2014
- The Autoimmune Basis of Alopecia Areata: A Comprehensive Review Autoimmunity reviews · 2014
- Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition Nature medicine · 2014
- The Dermal Papilla: An Instructive Niche for Epithelial Stem and Progenitor Cells in Development and Regeneration of the Hair Follicle Cold Spring Harbor Perspectives in Medicine · 2014
- NF-κB Activity Is Required for Anagen Maintenance in Human Hair Follicles In Vitro Journal of Investigative Dermatology · 2014
- In Vivo Transcriptional Governance of Hair Follicle Stem Cells by Canonical Wnt Regulators Nature Cell Biology · 2014
- Recent Advances in the Pathogenesis of Autoimmune Hair Loss Disease Alopecia Areata Clinical and Developmental Immunology · 2013
- Systemic Autoimmune Diseases: Insights and Advances Clinical and developmental immunology/Clinical & developmental immunology · 2013
- Autoimmune Disease Induction in a Healthy Human Organ: A Humanized Mouse Model of Alopecia Areata Journal of Investigative Dermatology · 2012
- Mesenchymal–Epithelial Interactions During Hair Follicle Morphogenesis and Cycling Seminars in Cell & Developmental Biology · 2012
- Brain And Muscle Arnt-Like Protein-1 (BMAL1) Controls Circadian Cell Proliferation And Susceptibility To UVB-Induced DNA Damage In The Epidermis Proceedings of the National Academy of Sciences of the United States of America · 2012
- Alopecia Areata: An Autoimmune Disease Causing Hair Loss The New England Journal of Medicine · 2012
- New Activators and Inhibitors in the Hair Cycle Clock: Targeting Stem Cells’ State of Competence Journal of Investigative Dermatology · 2012
- The Human Hair Follicle, A Bistable Organ? Experimental Dermatology · 2012
- Paracrine TGF-β Signaling Counterbalances BMP-Mediated Repression in Hair Follicle Stem Cell Activation Cell stem cell · 2012
- Calcitonin Gene-Related Peptide (CGRP) May Award Relative Protection from Interferon-γ-Induced Collapse of Human Hair Follicle Immune Privilege Experimental Dermatology · 2011
- Self-Organizing and Stochastic Behaviors During the Regeneration of Hair Stem Cells Science · 2011
- Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity Nature · 2010
- The Cycling Hair Follicle as an Ideal Systems Biology Research Model Experimental Dermatology · 2010
- The Mesenchymal Component of Hair Follicle Neogenesis: Background, Methods, and Molecular Characterization Experimental Dermatology · 2009
- The Hair Follicle as a Dynamic Mini-Organ Current Biology · 2009
- Neuroendocrinology of Epithelial Hair Follicle Stem Cells Molecular and Cellular Endocrinology · 2008
- Maintenance of Hair Follicle Immune Privilege Is Linked to Prevention of NK Cell Attack Journal of Investigative Dermatology · 2007
- Lymphocytes, Neuropeptides, And Genes Involved In Alopecia Areata Journal of Clinical Investigation · 2007
- Keratins of the Human Hair Follicle International review of cytology · 2005
- Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings · 2003
- The Follicular Automaton Model: Effect of Stochasticity and Synchronization of Hair Cycles Journal of theoretical biology · 2002
- Alopecia Areata: Gene Expression in Skin Samples from Patients Clinics in dermatology · 2001
- Modeling the Dynamics of Human Hair Cycles by a Follicular Automaton Proceedings of the National Academy of Sciences · 2000