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In this study, researchers developed a biodegradable microneedle made of hyaluronic acid, intended to enhance drug delivery through the skin's stratum corneum and potentially promote hair growth by overcoming the skin's barrier function in alopecia treatment.

This review discusses the application of active transdermal technologies in cosmetic devices for skin restoration and enhancement, reporting no new clinical results.

This study found that microneedling combined with calcipotriol plus betamethasone was more effective in treating vitiligo than microneedling with tacrolimus, particularly in difficult-to-treat areas.

This study found that polymeric nanoparticles retained more minoxidil and facilitated superior drug permeation compared to lipid nanoparticles, although premature drug release affected formulation performance.

This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.

This study found that encapsulated Garcinia mangostana Linn extract in a cream base penetrated more deeply and homogeneously into porcine ear skin compared to other formulations.

This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.

This article examines microscopic structural differences and pigment distribution in various rabbit hair colors and reports no clinical results.

This study found that in Colombian women with non-scarring alopecia, decreased serum ferritin levels were associated with telogen effluvium, but no such link was observed with thyroid disorders.

In this study, lecithin/n-propanol/isopropyl myristate/water/tetracaine hydrochloride microemulsion was found to be a safe carrier for transdermal drug delivery in animal models, with analgesic effects on Wistar rats.

This review discusses recent advances in skin penetration mechanisms, specifically focusing on the enhanced understanding of the follicular pathway and its implications for transdermal therapies, immune system targeting, and nanoparticle safety.

In this study, a new formulation of all-trans retinoic acid bound to polyvinyl alcohol showed reduced skin inflammation and sustained drug release for up to six days compared to free ATRA in vitro and in vivo.

In this study, desmopressin-loaded elastic liposomes (ODEL1) showed improved permeation and drug deposition across rat skin by altering the skin's cohesive energies and causing reversible changes on its surface.

This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.

This study developed a nanoemulsion containing Minoxidil, which showed effective stability and significantly increased hair growth rates in pretreated mice, suggesting its potential for treating hair loss.

Hormonal contraceptives are effective for teens but require careful consideration of side effects and individual health.

In this study, researchers found that in hairy guinea pig skin, minoxidil delivered via 40-nm nanoparticles had higher skin penetration than 130-nm nanoparticles, indicating nanoparticle size affects permeation.

In this study, transdermal application of anabolic steroids demonstrated rapid and extended detectability in urine, suggesting potential implications for doping control considerations.

Using molecular dynamics simulations, this study explored the uptake processes of JAK inhibitors on stratum corneum and hair follicle membranes, revealing a unique interaction mechanism in the hair follicle and offering insights into transdermal drug delivery pathways.

This study reported that a new polymeric formulation for topical minoxidil delivery in an animal model improved hair growth and hair follicle formation more effectively than minoxidil in PBS, suggesting potential as a future hair loss treatment.

This review discusses the design strategies and applications of long-acting polymeric microneedles, noting their potential to improve patient compliance and reduce side effects in chronic disease management, but reports no new experimental results.

This chapter reviews dermatological drugs and cosmetics, identifying common allergens and preservatives linked to contact dermatitis without reporting new clinical results.

This study found that IMT-P8, a novel cell-penetrating peptide, effectively facilitated the dermal delivery of proteins and peptides in mouse skin and cell lines, suggesting potential for topical applications in cosmetics and skin diseases.

This review highlights the potential of permeation enhancers to improve the delivery of active ingredients across the skin, optimizing therapeutic outcomes despite challenges posed by individual variability and environmental factors, according to the authors' analysis of current understanding and applications in skincare and transdermal therapies.

This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.

This review explores the use of topical and transdermal delivery for drugs and cosmetics, highlighting the benefits of avoiding side effects and rapid metabolism, with a focus on nanoparticulate formulations and techniques for studying skin penetration.

This review discusses the pathophysiology, diagnosis, and management of functional hypothalamic amenorrhea in adolescent girls and reports no new clinical results.

This review discusses the limitations of serum androgen measurements in diagnosing and treating women with potential androgen-related disorders and the potential role of androgen replacement therapy for those with sexual interest/arousal disorders, reporting no new results.

This study found that retinoic acid pre-treatment enhanced the efficiency of gene transfer into mouse skin for potential therapeutic applications.

This review discusses the role of skin enzymes in drug metabolism and emphasizes the need for models assessing enzyme activity to evaluate the safety and bioequivalence of topical generic drugs, highlighting efforts to standardize testing protocols for transdermal products.