Theoretical Investigation on the Construction of Hair Follicle Membranes and the Transdermal Drug Delivery Mechanisms of JAK Inhibitors via Distinct Pathways

    Zhaoli Jiang, Ying Li, Shiling Yuan
    Studysummary Using molecular dynamics simulations, this study explored the uptake processes of JAK inhibitors on stratum corneum and hair follicle membranes, revealing a unique interaction mechanism in the hair follicle and offering insights into transdermal drug delivery pathways.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sciencedirect.com →
    Discuss this study in the Community →

    Research cited in this study 3

    1. Complex Nanoemulsion for Vitamin Delivery: Droplet Organization and Interaction with Skin Membranes Nanoscale · 2021
    2. Assessment of Penetration of Ascorbyl Tetraisopalmitate Into Biological Membranes by Molecular Dynamics Computers in Biology and Medicine · 2016
    3. Penetration of Drugs Through Skin: A Complex Rate-Controlling Membrane 2012