TLDR 3D printing can make microneedles for drug delivery faster and cheaper.
The document reviewed the use of 3D printing technologies for manufacturing microneedles (MNs) aimed at enhancing transdermal drug delivery. It highlighted the advantages of 3D printing, such as creating personalized and cost-effective medical devices, and discussed various MN types, including hollow, solid, coated, dissolving, and swelling MNs. The review emphasized the potential of 3D printing to overcome traditional manufacturing limitations and addressed challenges in commercialization, such as material selection and regulatory issues. The document also explored different 3D printing methods, including FDM, SLA, DLP, and LCD, each offering unique benefits and challenges. Despite the promise of MNs, further research was needed to optimize 3D printing technologies and ensure safe and effective MN devices.
26 citations
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June 2020 in “Polymers” Microneedle made of iron oxide and PVA helps hair regrowth in alopecia treatment.
166 citations
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February 2020 in “Advanced Functional Materials” The smart bandage improved healing in diabetic mice by delivering drugs directly into wounds.
149 citations
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September 2017 in “Pharmaceutics” Pig skin is a good substitute for human skin to measure drug absorption, but differences in skin structure and enzymes across species must be considered.
81 citations
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October 2023 in “Bioactive Materials” 3D-printed microneedles improve drug delivery and diagnostics but face scalability and regulatory challenges.
12 citations
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November 2022 in “Cosmetics” 3D printed microneedles are likely to become more common in cosmetics for better skin delivery.
1 citations
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August 2023 in “Advanced Drug Delivery Reviews” Microneedles are promising for long-acting drug delivery and can improve patient compliance, but more data is needed to confirm their effectiveness.
46 citations
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January 2020 in “Research” Microneedle technology has advanced for painless drug delivery and sensitive detection but faces a gap between experimental use and clinical needs.
14 citations
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December 2024 in “Pharmaceutics” Hydrogel microneedles offer a promising, minimally invasive way to treat diseases like cancer and hair loss, but need improvements in strength and standardization.
