3D Printing: A Touch-Button Approach to Manufacture Microneedles for Transdermal Drug Delivery

June 2021 in “ Pharmaceutics ”

Merima Sirbubalo, Amina Tucak, Kenan Muhamedagić, Lamija Hindija, Ognjenka Rahić, Jasmina Hadžiabdić, Ahmet Çekiç, Đerzija Begić-Hajdarević, Maida Cohodar, Almir Dervišević, Edina Vranić

microneedles transdermal drug delivery 3D printing drug delivery systems

Studysummary This review summarizes the use of 3D printing technologies for creating microneedles and evaluates their associated benefits, challenges, and regulatory considerations, but does not present new experimental results.

Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer

The document reviewed the use of 3D printing technologies for manufacturing microneedles (MNs) aimed at enhancing transdermal drug delivery. It highlighted the advantages of 3D printing, such as creating personalized and cost-effective medical devices, and discussed various MN types, including hollow, solid, coated, dissolving, and swelling MNs. The review emphasized the potential of 3D printing to overcome traditional manufacturing limitations and addressed challenges in commercialization, such as material selection and regulatory issues. The document also explored different 3D printing methods, including FDM, SLA, DLP, and LCD, each offering unique benefits and challenges. Despite the promise of MNs, further research was needed to optimize 3D printing technologies and ensure safe and effective MN devices.

View this study on mdpi.com →

Discuss this study in the Community →

Research cited in this study

3 / 3 results

research Transdermal Composite Microneedle Composed of Mesoporous Iron Oxide Nanoraspberry and PVA for Androgenetic Alopecia Treatment

26 citations , June 2020 in “Polymers”

This study reported that a magneto-responsive transdermal microneedle system delivered Minoxidil effectively and significantly increased hair density by 800% in mice with androgenetic alopecia after 10 days.

research A Wirelessly Controlled Smart Bandage with 3D-Printed Miniaturized Needle Arrays

166 citations , February 2020 in “Advanced Functional Materials”

This study reports that a novel programmable device delivering VEGF through miniaturized needles significantly improved healing outcomes in diabetic mice's chronic wounds compared to traditional topical treatments.

research Transdermal Permeation of Drugs in Various Animal Species

149 citations , September 2017 in “Pharmaceutics”

This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.