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In this study, researchers found that mice lacking the transcription factor FOXC1 in their hair follicle stem cells had increased rounds of hair regeneration but experienced hair thinning due to impaired ability to maintain stem cell quiescence and adhesion.

This review reports that combining adipose-derived stem cells with decellularized extracellular matrix enhances tissue repair by improving scaffold biological activity and promoting angiogenesis, integration, and functional regeneration across various tissues, while addressing challenges in traditional transplantation methods.

This review found that combining adipose-derived tissues and platelet-rich plasma improves fat graft survival and healing outcomes in reconstructive and aesthetic surgery, but variability in methodologies limits study comparability.

This study conducted in Yemen involving 50 patients found that tissue expansion was effective for correcting scars and defects from post-burn and post-war injuries, achieving a 78% satisfaction rate with minimal complications.

Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.

In this systematic review, various nutrients and diets, such as a plant-based diet and supplements like omega-3 fatty acids, were found to impact tissue regeneration, skin health, and wound healing, highlighting the role of nutrient-sensitive signaling pathways in these processes.

This study highlights keratin biomaterials as a promising biocompatible option for wound healing and tissue regeneration but notes that further clinical studies are necessary to confirm their effectiveness.

This review discusses the use of adipose tissue and platelet-rich plasma in tissue repair and regeneration, noting their promise in surgical outcomes but emphasizing the need for further research to optimize therapies.

New methods using biomaterials, stem cells, and nanoparticles show promise for improving hair growth and treating hair loss.

This study constructed a 3D-printed scaffold using sodium alginate, gelatin, and alginate lyase hydrogel, which supports hair follicle regeneration in artificial skin, suggesting a promising strategy for tissue-engineered skin with functional appendages.

This study found that patients with trichodynia associated with androgenetic alopecia had significantly higher levels of substance P in both tissue and serum compared to healthy controls, suggesting a potential role for this neurotransmitter in the condition's pathogenesis.

This study developed a novel zinc-releasing hydrogel, Zn-Gel, which promoted wound healing by controlling zinc ion release and demonstrated excellent compatibility and efficacy in enhancing cell proliferation, blood vessel formation, and tissue regeneration in vitro and in vivo settings.

This review explores the critical role of stem cells in body maintenance and their potential in regenerative medicine, highlighting their impact on aging and rare diseases and examining their influence on various body systems and the therapeutic potential of exosomes.

This study found that using overexpanded tissue expanders effectively restored the hairy scalp in 25 patients with scalp alopecia, resulting in high satisfaction and minimal complications, emphasizing the importance of careful patient selection and follow-up.

This case report detailed a successful treatment involving contracture release and expanded neck flap reconstruction for a patient with severe neck contracture and beard alopecia from past thermal burns, highlighting improved skin quality and hair regrowth following follicular unit extraction.

This study found that topical application of TGF-β mimic promoted enhanced wound healing and tissue regeneration in mice, suggesting its potential as a therapeutic option for improving wound healing.

This study found that toll-like receptor 9 plays a previously unrecognized role in sensing skin injury and influencing tissue repair and regeneration in adult mice by modulating γδT cell migration.

This study found that stem cell therapy before follicular unit extraction may improve hair restoration outcomes on scarred scalp tissue.

In this case study, a patient developed parieto-temporal pain, tissue necrosis, and alopecia after receiving a hyaluronic acid injection for temporal augmentation, which was effectively treated with hyaluronidase and aspirin.

Quickly fix tissue in formalin after excision to preserve it.

This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.

This review explores the potential of non-invasive photobiomodulation therapy for managing combat and traumatic soft tissue injuries, emphasizing its benefits, efficacy, and underlying mechanisms, but reports no new clinical results.

In a rat scalp expansion model, this study found that activating autophagy with rapamycin enhanced skin regeneration during tissue expansion by increasing expanded skin area, epidermis and dermis thicknesses, cell proliferation, angiogenesis, and other regenerative factors, whereas blocking autophagy reversed these effects.

This study developed a degradable and bioactive citrate-based polyurethane adhesive that achieves rapid and strong tissue adhesion, exhibiting improved bonding strength in wet environments, biocompatibility, biodegradability, and hemostatic properties, with potential to enhance wound healing by promoting angiogenesis.

This source reviews the potential of 3D printing, biomaterials, and smart sensors in tissue engineering, noting their application in creating artificial membranes for skin and tissue regeneration and assessing their strengths and limitations for wound dressing development and disease modeling.

This research explored the roles of various T cell types in chronic alopecia areata, finding that increased severity of lesions and hair loss may be linked to decreased lesional Foxp3+ Tregs, with a notable role for IL-17 and Th17 lymphocytes in the pathological process.

This review discusses techniques for repairing large scalp defects, emphasizing the combination of older methods like scalp reduction and tissue expansion with modern hair restoration surgery to achieve satisfactory results, despite challenges like compromised scalp viability due to factors like trauma or radiation.

In this study, researchers using live mice observed that oncogenic Kras mutation disrupts hair follicle architecture by sustaining ERK signal activation, which affects stem cell behavior and tissue integrity.

This study found that the KrasG12D mutation alters ERK signal dynamics in hair follicle stem cells, leading to tissue deformation, and suggests a collective effect of mutant cells is necessary for disruption.