research Patent Reports
New patents include innovations in skin and hair care, disease treatment, plant stress tolerance, and protein purification.
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research The Influence of 3% Hydrogen Peroxide on the Survival Rate of Hair Grafts When Used as an Antiseptic Solution for Surgical Wound Care: Experience with Five Patients
3% hydrogen peroxide does not reduce hair graft survival compared to saline.
research Dermatological Drugs and Topical Agents
Certain skin drugs and topical agents, including some natural extracts and fragrances, can cause allergic reactions. Some hair dyes and extensions, as well as minoxidil, a hair growth treatment, can also cause allergies. Botulinum toxin A can effectively reduce sweat but may have temporary side effects.
research Factors to Consider When Selecting Antiulcer Drugs for a Formulary
The document concludes that H2-antagonists and proton pump inhibitors are highly effective for ulcers, eradicating Helicobacter pylori is important to prevent recurrence, and misoprostol helps with NSAID-related ulcers.
research 8th Postgraduate Seminar in Pediatric Dermatology
Experts discussed treatments for skin conditions in children, emphasizing hydration, cautious medication use, and early intervention for infections.
research Nanoparticles Enhance Therapeutic Outcome in Inflamed Skin Therapy
Nanoparticles improve drug delivery and effectiveness in treating inflamed skin.
research Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure
Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
research Effective Detoxification of Abrus Precatorius Linn. Seeds by Shodhana
The detoxification process made Abrus precatorius seeds safe and effective for use.
research An Overview of the Role of Carboxytherapy in Dermatology
Carboxytherapy is a safe and effective treatment for improving skin appearance and treating various skin conditions, with mild side effects.
research The Inflammatory Component of Androgenetic Alopecia
Androgenetic alopecia, a genetic disorder affecting up to 50% of adults, is caused by an excessive response to androgens leading to hair follicle shrinkage. Treatments include FDA-approved drugs, other therapies like low-dose oral minoxidil, and hair transplantation.
research Identification of Immune Microenvironment Changes, Immune-Related Pathways and Genes in Male Androgenetic Alopecia
The research suggests immune system changes and specific gene expression may contribute to male hair loss, proposing potential new treatments.
research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition
Alopecia areata can be reversed by JAK inhibitors, promoting hair regrowth.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
research Improved Health-Span and Lifespan in mtDNA Mutator Mice Treated with the Mitochondrially Targeted Antioxidant SkQ1
SkQ1 antioxidant improved health and lifespan in mice.
research Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation
The study found that ornithine decarboxylase 1 (Odc1) was regulated by the androgen receptor (AR) in skeletal muscle, with higher expression in adult male mice compared to females and younger males. Odc1 was essential for myoblast proliferation, as its inhibition reduced myoblast numbers, while overexpression increased them. AR deletion in mice led to decreased Odc1 expression, indicating direct regulation by AR. Dihydrotestosterone (DHT) also upregulated Odc1 in human myoblasts, supporting its role in proliferation. These findings suggested that androgens, through AR, contributed to greater muscle mass in males and normal muscle development, with potential therapeutic implications for enhancing muscle mass in conditions like HIV, cancer cachexia, and sarcopenia. ODC was already a target for treating hirsutism, indicating the potential for developing ODC agonists to increase muscle mass without androgen side effects.
research Skin and Hair Cosmetic Issues in Women of Color
A scarring hair loss condition mainly affects middle-aged women of African descent, impacting their quality of life, with treatments more effective when started early.
research Inhibition of Mitochondrial Respiration Prevents BRAF-Mutant Melanoma Brain Metastasis
Stopping mitochondrial respiration can prevent brain cancer spread in skin cancer patients, and plant compound β-sitosterol could help achieve this.
research Psoriasis Is Characterized by Deficient Negative Immune Regulation Compared to Transient Delayed-Type Hypersensitivity Reactions
Psoriasis may be chronic because it lacks certain immune system controls that prevent overreaction.
research Clinical Profile of Androgenic Alopecia and Its Association with Cardiovascular Risk Factors
Men with early-onset hair loss have more heart disease risk factors.
research Efficacy and Safety of an Oral Nutritional Supplement Containing Pinus Pinaster Bark Extract and Grape Seed Extract in Combination with a High SPF Sunscreen in the Treatment of Mild-to-Moderate Melasma: A Prospective Clinical Study
The oral supplement with Pinus pinaster and Grape seed extract, used with sunscreen, effectively and safely improved mild-to-moderate facial melasma.
research Birth, Life, and Death of the MAGE3 Hypothesis of Alopecia Areata Pathobiology
The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
research Update on Trichodynia, a Challenge for Dermatologists
Trichodynia is a painful scalp condition linked to hair loss and mental health issues, with limited treatment options.
research Supplementation of Amra Beej Majja Churna in Vitamin B12 Deficiency: A Case Study
Amra Beej Majja Churna may help improve Vitamin B12 levels and symptoms in vegans.
research ILC1-Like Innate Lymphocytes in Human Autoimmunity: Lessons from Alopecia Areata
ILC1-like cells can cause alopecia areata by disrupting hair follicle immunity, suggesting a new treatment approach.
research Superficial Cryotherapy: Does It Work in Alopecia Areata?
Superficial cryotherapy is effective and safe for treating alopecia areata, especially eyebrow hair loss.
research Therapeutic Efficacy of TriCell CD34+ Cell-Containing, Platelet-Rich Plasma in Alopecia Patients
TriCell CD34+ cell-containing PRP therapy improves hair thickness and density in alopecia patients without side effects.
research Pharmacopuncture and Dermal Application of Sebalgukhwa-San: Effects on Hair Growth in a Mouse Model of Alopecia
Sebalgukhwa-san (SGS) can help treat hair loss without liver toxicity.
research Development of New Treatment Modality for Male Infertility Using Phytopharmaceuticals
MOTILIPERM may help treat male infertility by reducing stress in cells.
research Retinoids Modulate MITF: A Novel Mechanism in the Regulation of Melanogenesis
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
research Antiepileptogenic Effects of Trilostane in the Kainic Acid Model of Temporal Lobe Epilepsy
Trilostane may help delay epilepsy development by increasing certain brain chemicals.