Ornithine Decarboxylase Is Upregulated by the Androgen Receptor in Skeletal Muscle and Regulates Myoblast Proliferation

    April 2011 in “ AJP Endocrinology and Metabolism ”
    Nicole K. L. Lee, Jarrod P. Skinner, Jeffrey D. Zajac, Helen E. MacLean
    Studysummary This study found that androgens increase Odc1 expression in skeletal muscle myoblasts, promoting proliferation and delaying differentiation.
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    Research cited in this study 4

    1. Medical Treatment of Hirsutism Dermatologic therapy · 2008
    2. Anabolic Effects of Testosterone Are Preserved During Inhibition of 5α-Reductase Endocrinology and metabolism/American journal of physiology: endocrinology and metabolism · 2007
    3. Potential Adverse Effects of Long-Term Testosterone Therapy Baillière's clinical endocrinology and metabolism · 1998
    4. Ornithine Decarboxylase Overexpression Is a Sufficient Condition for Tumor Promotion in Mouse Skin PubMed · 1997