The Mechanisms of Anabolic Steroids, Selective Androgen Receptor Modulators, and Myostatin Inhibitors
June 2022
in “
대한스포츠의학회지
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TLDR Anabolic steroids boost muscle growth, SARMs increase muscle mass and bone density without side effects, and myostatin inhibitors block a protein that stops muscle growth, but each has potential risks.
The document discusses the mechanisms of anabolic steroids, selective androgen receptor modulators (SARMs), and myostatin inhibitors. Anabolic steroids like testosterone induce muscle hypertrophy by up-regulating androgen receptors in skeletal muscle. SARMs, such as YK11, selectively stimulate the androgen receptors in muscle and bone, increasing muscle mass and bone density without the side effects of traditional anabolic steroids. Myostatin inhibitors increase muscle mass and strength by blocking the activity of myostatin, a protein that inhibits muscle growth. However, there are potential adverse effects: hypogonadism risk with anabolic steroids, unknown long-term effects of SARMs, and potential tendon brittleness with myostatin inhibitors.