Beyond Testosterone Cypionate: Evidence Behind the Use of Nandrolone in Male Health and Wellness

The 2016 review article explored the use of nandrolone, an anabolic steroid, for male health issues, highlighting its potential for muscle growth and joint healing, with a particular interest in its effects on alopecia in male hypogonadism. Nandrolone may promote muscle mass more effectively than testosterone with fewer side effects. It has been used to treat conditions like anorexia and cachexia, resulting in increased lean body mass and strength. However, its use could lead to erectile dysfunction due to HPG axis suppression and increased serum estrogens. The lack of conversion to DHT suggests it might reduce hair loss in men on testosterone replacement therapy. Despite these potential benefits, the review emphasized the need for more human studies to confirm nandrolone's therapeutic applications, as research was limited at the time of publication.