Long-Term Differential Changes in Mouse Intestinal Metabolomics After Gamma and Heavy Ion Radiation Exposure

    January 2014 in “ PLOS ONE
    Amrita K. Cheema, Shubhankar Suman, P. Kaur, Rajbir Singh, Albert J. Fornace, Kamal Datta
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    TLDR Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.
    The 2014 study "Long-Term Differential Changes in Mouse Intestinal Metabolomics after γ and Heavy Ion Radiation Exposure" involved 60 mice and investigated the long-term effects of gamma and heavy ion radiation on the intestinal metabolomics of mice. The results showed that both types of radiation caused significant changes in the intestinal metabolomics, with the effects being more pronounced and lasting longer in the mice exposed to heavy ion radiation. Specifically, heavy ion radiation caused a long-term increase in the levels of certain metabolites, such as amino acids, nucleotides, and lipids. The study concluded that heavy ion radiation has a more severe and long-lasting impact on intestinal metabolomics than gamma radiation.
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