Efficacy and Safety of an Oral Nutritional Supplement Containing Pinus Pinaster Bark Extract and Grape Seed Extract in Combination with a High SPF Sunscreen in the Treatment of Mild-to-Moderate Melasma: A Prospective Clinical Study

    March 2019 in “ Cosmetics ”
    Sonia Aladrén, Aurora Garre, Palmira Valderas-Martínez … Corinne Granger
    Studysummary In this study, a combined regimen of an oral supplement with Pinus pinaster, Grape seed extract, vitamins, and minerals, plus high SPF sunscreen, significantly improved mild-to-moderate facial melasma in 30 women over 84 days, reducing pigmentation and enhancing cosmetic appearance with no reported adverse effects.
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    Research cited in this study 1

    1. Melasma, A Photoaging Disorder Pigment cell & melanoma research · 2017