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    Glossary Stratum Granulosum

    layer where skin cells start to die and form keratin

    The Stratum Granulosum, also known as the Granular Layer, is a thin layer of cells in the epidermis, the outermost part of the skin. It is situated between the Stratum Spinosum and the Stratum Corneum. In this layer, keratinocytes begin to die and form a waterproof barrier by producing keratin and lipids, which are essential for skin hydration and protection against external pathogens.

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    1. 1299 Live imaging of keratin network in stratum granulosum reveals dynamic cytoskeletal changes during cornification in mice in vivo Journal of Investigative Dermatology · 2018
    2. The role of tight junctions in skin barrier function and dermal absorption Journal of controlled release · 2016 · 156 citations
    3. Isolation and Characterization of Human Repetin, a Member of the Fused Gene Family of the Epidermal Differentiation Complex Journal of Investigative Dermatology · 2005 · 77 citations
    4. A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification 2002 · 66 citations
    5. EFFECTS OF STEROID HORMONES ON DEVELOPING MOUSE SKIN IN VITRO Journal of Endocrinology · 1975 · 6 citations
    6. Histology, lectin histochemistry and ultrastructure of interdigital gland in crossbred sheep 2020 · 3 citations
    7. Effects of Acute UVB on Retinoid Metabolism ˜The œFASEB journal · 2015 · 1 citations
    8. Four murine monoclonal antibodies specific for the inner root sheath in the human hair follicle 1989 · 1 citations
    9. Histological Study for Skin of Horse 2023
    10. LB1081 Three-dimensional imaging of tight junction-network across multiple layers of human epidermis by array tomography using backscattered electron-mode scanning electron microscopy Journal of Investigative Dermatology · 2019
    11. Expression of retinoid-X receptors (-Æ,-a,-a) and retinoic acid receptors (-Æ,-a,-a) in normal human skin: an immunohistological evaluation 1997
    12. Epidermal Barrier Cosmetic Dermatology · 2022
    13. Histomorphological study on the teat (mammary papilla) of Indian buffalo The Indian Journal of Animal Sciences · 1995 · 7 citations
    14. A Spontaneous Fatp4/Scl27a4 Splice Site Mutation in a New Murine Model for Congenital Ichthyosis PLoS ONE · 2012 · 13 citations
    15. Glycerol Regulates Stratum Corneum Hydration in Sebaceous Gland Deficient (Asebia) Mice Journal of Investigative Dermatology · 2003 · 216 citations
    16. Penetration of drugs through skin, a complex rate-controlling membrane 2012 · 211 citations
    17. Biocompatible nanoparticles and vesicular systems in transdermal drug delivery for various skin diseases International Journal of Pharmaceutics · 2018 · 151 citations
    18. Delivery and targeting of nanoparticles into hair follicles Therapeutic Delivery · 2014 · 94 citations
    19. IMPROVED SKIN PENETRATION AND DEPOSITION OF NAFTIFINE FROM TRANSETHOSOMES AND TRANSETHOSOMAL GEL FORMULATIONS FARMACIA · 2022 · 12 citations
    20. The Fate of Epidermal Tight Junctions in the stratum corneum: Their Involvement in the Regulation of Desquamation and Phenotypic Expression of Certain Skin Conditions International Journal of Molecular Sciences · 2022 · 11 citations
    21. Morphological characteristics and notes of the skin in preclinical toxicity assessment Journal of toxicologic pathology · 2022 · 2 citations
    22. Combined Ultrasound and Microneedle for Enhanced Transdermal Delivery: Synergistic Mechanisms and Therapeutic Advances BIO Integration · 2025 · 1 citations
    23. Microneedles-A new paradigm in transdermal delivery of therapeutic agents Pharmaceutical Sciences Asia · 2022 · 1 citations
    24. Influence of donor sources and culture media on the histo-morphological quality of human artificial skin models Online Publication Service of Würzburg University (Würzburg University) · 2018
    25. Ablative Fractional Resurfacing in Topical Drug Delivery: An Update and Outlook Dermatologic Surgery · 2013 · 55 citations
    26. Particularidades dermatológicas, fisiológicas e as dermatoses na pele negra Revista Eletrônica Acervo Saúde · 2024 · 1 citations
    27. Recent advances in X-ray microanalysis in dermatology. PubMed · 1985 · 10 citations
    28. Do nanoparticles have a future in dermal drug delivery? Journal of Controlled Release · 2016 · 87 citations
    29. Epidermal mammalian target of rapamycin complex 2 controls lipid synthesis and filaggrin processing in epidermal barrier formation Journal of Allergy and Clinical Immunology · 2019 · 34 citations
    30. Tight junctions form a barrier in porcine hair follicles European journal of cell biology · 2015 · 21 citations