Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment

    December 2022 in “ Journal of toxicologic pathology ”
    Takayasu Moroki
    Studysummary This review outlines the histological structures of the skin, highlighting species and regional differences in dermal absorption and obstacles encountered in toxicological assessments due to epidermal thickness variability, contact dermatitis reactions, and stem cell vulnerabilities.
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    Research cited in this study 8

    1. A Clinical and Biological Guide for Understanding Chemotherapy-Induced Alopecia and Its Prevention Oncologist · 2017
    2. Morphological Analysis of Patchy Thickening and Reddish Discoloration of Active Hair Growth Areas in the Skin of New Zealand White Rabbits Journal of toxicologic pathology · 2017
    3. Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument Journal of toxicologic pathology · 2013
    4. Review of Hair Follicle Dermal Cells Journal of Dermatological Science · 2009
    5. Gene Expression Profiling Gets to the Root of Human Hair Follicle Stem Cells ˜The œJournal of clinical investigation/˜The œjournal of clinical investigation · 2005
    6. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005
    7. Short Anagen Hair With Persistent Synchronized Pattern of Scalp Hair Growth Journal of The American Academy of Dermatology · 2003
    8. Hair Follicle Stem Cells: Insights from the 2003 Workshop ˜The œjournal of investigative dermatology. Symposium proceedings/˜The œJournal of investigative dermatology symposium proceedings · 2003

    Related research 2

    1. Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment Journal of toxicologic pathology · 2022
    2. An Improved and Rapid Method to Construct Skin Equivalents from Human Hair Follicles and Fibroblasts Experimental dermatology · 2001