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    GlossarySkin Permeation (Dermal Absorption)

    process where substances pass through skin into bloodstream

    Skin permeation, also known as transdermal absorption or percutaneous absorption, refers to the process by which substances pass through the skin and enter the bloodstream. This process involves the movement of molecules through the outermost layer of the skin (the stratum corneum), into the deeper layers, and eventually into the circulatory system. It is a critical concept in dermatology and pharmacology, particularly for the development of topical medications and transdermal drug delivery systems.

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      a signaling molecule from dermal papilla cells being actively researched
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      community Is microneedling + minoxidil better than oral minoxidil

      in Chat  29 upvotes 2 months ago
      Oral minoxidil is considered more effective for hair regrowth than topical minoxidil, but it carries higher risks. Combining microneedling with topical minoxidil can enhance absorption, but oral minoxidil with microneedling shows significant results.
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      community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year

      in Research/Science  735 upvotes 2 years ago
      A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.

      community Vitamin C and hair growth PH levels

      in Product  31 upvotes 2 years ago
      The conversation is about using vitamin C and Magnesium L-Threonate for hair growth by reducing DHT binding to dermal papilla cells. The original post about vitamin C's pH levels and sebum control was possibly removed by a moderator.