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GlossaryKeratohyalin Granules

tiny structures in skin cells aiding keratin production

Keratohyalin granules are tiny structures found in the cells of the outer layer of the skin, specifically in the stratum granulosum. They play a crucial role in the process of keratinization, where skin cells produce keratin, a protein that helps form a protective barrier. These granules contain proteins like filaggrin, which help in the aggregation of keratin filaments, contributing to the skin's strength and resilience.

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research Histological Changes of Pre and Postnatal Skin Development in Rats

January 2012

Rat skin develops from a single layer to adult-like skin with hair follicles by day 21.

research Ultrastructure of the Contrasting Types of Keratinization Seen in the Tail Epidermis of the Laboratory Mouse Mus Musculus

11 citations , January 1977 in “Archives of dermatological research”

Mouse tail skin has different keratinization near hair follicles and scales.

research Spiny Keratoderma: A Demonstration of Hair Keratin and Hair Type Keratinization

30 citations , January 1999 in “Journal of Cutaneous Pathology”

Spiny keratoderma may be ectopic hair formation on palms and soles.

research Impact of Constant Light Exposure During Pregnancy on Skin of Neonatal New Zealand Rabbits: Structural and Ultrastructural Study

1 citations , January 2021 in “Brazilian Journal of Medical and Biological Research”

Constant light exposure during pregnancy changes newborn rabbits' skin, affecting hair follicles, skin thickness, and pigment cells.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

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