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Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.

The compound 4c effectively inhibits the enzyme linked to hair loss.

New steroidal compounds could be effective for treating conditions related to 5α-reductase enzyme activity.

Men taking dutasteride or finasteride have a slightly higher risk of developing type 2 diabetes.

Benzo[c]quinolizin-3-ones are effective nonsteroidal inhibitors of human steroid 5α-reductase 1.

Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.

Researchers developed a new method to find substances in herbs that can block a specific enzyme linked to hair loss.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Ocimum basilicum L. and red Oryza sativa L. may help with hair loss and prostate issues.

Compound 4 is a promising treatment for hair loss with low toxicity.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Finasteride effectively blocks enzyme causing male pattern baldness.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Gene differences may affect baldness treatment response in Korean men.

Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

Certain natural compounds can block an enzyme linked to prostate enlargement and hair loss, showing potential for new treatments.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.

Selective non-steroidal inhibitors of 5α-reductase type 1 can help treat DHT-related disorders.

FCE 28260 is a stronger and longer-lasting inhibitor of 5α-reductase than finasteride, which may make it a better treatment for certain medical conditions.

Certain drugs that block specific enzymes can help treat prostate diseases.

A reliable model for screening type II 5α-reductase inhibitors was created and validated.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.

Finasteride's effect on hair loss and prostate enlargement depends on its binding to an enzyme, with maximum impact at 0.2 mg dose.

Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.

Certain drugs change freshwater snail shells to a "banana" shape.