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    GlossaryNonsteroidal Inhibitors

    compounds that block biological processes without using steroids

    Nonsteroidal inhibitors are compounds that block specific biological processes without using steroid structures. In the context of hair and alopecia, these inhibitors can target enzymes or pathways involved in hair loss, such as 5-alpha-reductase, which converts testosterone to dihydrotestosterone (DHT), a hormone linked to hair thinning and loss.

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      learn Bicalutamide

      a nonsteroidal anti-androgen, most commonly used orally for women

      learn Fluridil

      a topical anti-androgen with less systemic involvement

      learn Pyrilutamide

      highly targeted anti-androgen that might have minimal systemic effects

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      community So we’re just ok with taking a research chemical now?

      in Treatment  179 upvotes 3 years ago
      The conversation discusses the use of RU58841, a non-FDA approved research chemical for hair loss, with mixed opinions on its safety and effectiveness. Some users are willing to try it as a last resort after other treatments like Minoxidil and Finasteride failed, while others express concerns about potential long-term side effects and lack of official research.

      community KX-826 Pyrilutamide1% coming soon

      in Update  152 upvotes 4 months ago
      KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.

      community Medications that cause extra hair growth

      in Research/Science  123 upvotes 1 year ago
      The post discusses the side effects of various drugs causing excess hair growth, questioning why only minoxidil is used in the hair loss industry. The conversation includes users sharing their experiences and concerns about potential side effects of these drugs, with some preferring baldness over potential health risks.

      community Been on Min and Fin for Years and I am Devastated.

      in Treatment  64 upvotes 2 years ago
      Guyman567 has been using oral finasteride and topical minoxidil for years but continues to experience hair loss and thinning, which has affected his confidence. He has tried various treatments including topical finasteride, microneedling, and vitamins, and is considering a hair transplant but is concerned about ongoing hair loss.