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    Glossary Proxalutamide

    experimental drug blocking male hormone effects

    Proxalutamide is an experimental drug that acts as a nonsteroidal antiandrogen, meaning it blocks the effects of androgens (male hormones) like testosterone. It is being studied for its potential use in treating conditions like prostate cancer and androgenetic alopecia (a common form of hair loss), by inhibiting the androgen receptors that contribute to these conditions.

    Research 10 of 34

    1. Proxalutamide Reduces the Rate of Hospitalization for COVID-19 Male Outpatients: A Randomized Double-Blinded Placebo-Controlled Trial Frontiers in Medicine · 2021 · 42 citations
    2. Proxalutamide Significantly Accelerates Viral Clearance and Reduces Time to Clinical Remission in Patients with Mild to Moderate COVID-19: Results from a Randomized, Double-Blinded, Placebo-Controlled Trial Cureus · 2021 · 41 citations
    3. Final Results of a Randomized, Placebo-Controlled, Two-Arm, Parallel Clinical Trial of Proxalutamide for Hospitalized COVID-19 Patients: A Multiregional, Joint Analysis of the Proxa-Rescue AndroCoV Trial Cureus · 2021 · 19 citations
    4. Proxalutamide Improves Inflammatory, Immunologic, and Thrombogenic Markers in Mild-to-Moderate COVID-19 Males and Females: an Exploratory Analysis of a Randomized, Double-Blinded, Placebo-Controlled Trial Early Antiandrogen Therapy (EAT) with Proxalutamide (The EAT-Proxa Biochemical AndroCoV-Trial) medRxiv (Cold Spring Harbor Laboratory) · 2021 · 5 citations
    5. Proxalutamide (GT0918) Reduces the Rate of Hospitalization in mild-to-moderate COVID-19 Female Patients: A Randomized Double-Blinded Placebo-Controlled Two-Arm Parallel Trial medRxiv (Cold Spring Harbor Laboratory) · 2021 · 5 citations
    6. Proxalutamide Reduction of Mortality Rate in Hospitalized COVID-19 Patients Depends on Treatment Duration – an Exploratory Analysis of the Proxa-Rescue AndroCoV Trial bioRxiv (Cold Spring Harbor Laboratory) · 2021 · 5 citations
    7. Efficacy and safety of proxalutamide (GT0918) in severe or critically ill patients with COVID-19: study protocol for a prospective, open-label, single-arm, single-center exploratory trial BMC Pharmacology and Toxicology · 2023
    8. Expression of concern: potential risk for developing severe COVID-19 disease among anabolic steroid users BMJ case reports · 2021 · 21 citations
    9. An update of anti-viral treatment of COVID-19 Turkish Journal of Medical Sciences · 2021 · 51 citations
    10. Do Anti-androgens Have Potential as Therapeutics for COVID-19? Endocrinology · 2021 · 18 citations
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