research Two Mechanisms Regulate Keratin K15 Expression in Keratinocytes: Role of PKC/AP-1 and FOXM1 Mediated Signaling
Keratin 15 expression in skin cells is regulated by two mechanisms involving PKC/AP-1 and FOXM1.
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research Shedding Light on the Effects of Calorie Restriction and Its Mimetics on Skin Biology
Eating fewer calories may slow skin aging and improve skin health through various biological changes.
research Study of Drug Target Identification and Associated Molecular Mechanisms for the Therapeutic Activity and Hair Follicle Induction of Two Ashwagandha Extracts Having Differential Withanolide Constitutions
One Ashwagandha extract may help protect cells with its antioxidant properties, while another could promote hair growth.
research Systematic Review of Exosome Treatment in Hair Restoration: Preliminary Evidence, Safety, and Future Directions
Exosome treatment for hair growth is promising but not FDA-approved and needs more research on safety and how it works.
research Functional Hair Follicle Regeneration: An Updated Review
Hair follicle regeneration possible, more research needed.
research MSCs and Their Exosomes: A Rapidly Evolving Approach in the Context of Cutaneous Wound Therapy
MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.
research Locally Delivered Umbilical Cord Mesenchymal Stromal Cells Reduce Chronic Inflammation in Long-Term Nonhealing Wounds: A Randomized Study
Umbilical cord cells safely improve healing in long-term nonhealing wounds better than a placebo.
research Advancing Regenerative Cellular Therapies in Non-Scarring Alopecia
Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.
research Glycosaminoglycans’ Ability to Promote Wound Healing: From Native Living Macromolecules to Artificial Biomaterials
Glycosaminoglycans help heal wounds but aren't yet ready for clinical use.
research Tiny Messengers, Big Results: A Review of Exosome-Mediated Treatments and Considerations in Dermatology
Exosome therapy shows promise for treating skin conditions and improving wound healing.
research Analysis of Hidradenitis Suppurativa-Linked Mutations in Four Genes and the Effects of PSEN1-P242LfsX11 on Cytokine and Chemokine Expression in Macrophages
The document concludes that certain mutations may contribute to the inflammation in hidradenitis suppurativa and suggests that targeting TNFα could be a treatment strategy.
research The Role of PPARγ-Mediated Signalling in Skin Biology and Pathology: New Targets and Opportunities for Clinical Dermatology
PPARγ is crucial for skin health but can have both beneficial and harmful effects.
research Mice Lacking the Epidermal Retinol Dehydrogenases SDR16C5 and SDR16C6 Display Accelerated Hair Growth and Enlarged Meibomian Glands
Mice without certain skin enzymes have faster hair growth and bigger eye glands.
research Shedding Light on Cashmere Goat Hair Follicle Biology: From Morphology Analyses to Transcriptomic Landscape
The research found genes that change during cashmere goat hair growth and could help determine the best time to harvest cashmere.
research Hairy Tale of Signaling in Hair Follicle Development and Cycling
Hair growth and development are controlled by specific signaling pathways.
research Mesenchymal Stem Cells Isolated From Equine Hair Follicles Using A Method Of Air-Liquid Interface
Scientists found a new, less invasive way to get stem cells from horse hair for veterinary medicine.
research Melanocyte Stem Cells: A Melanocyte Reservoir in Hair Follicles for Hair and Skin Pigmentation
Melanocyte stem cells in hair follicles are key for hair color and could help treat greying and pigment disorders.
research Epidermal Stem Cells in Wound Healing and Their Clinical Applications
Epidermal stem cells help heal severe skin wounds and have potential for medical treatments.
research Application of Mesenchymal Stem Cells for Anti-Senescence and Clinical Challenges
Mesenchymal stem cells could help treat aging-related diseases better than current methods.
research Integration of Biochemical and Mechanical Signals at the Nuclear Periphery: Impacts on Skin Development and Disease
The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.
research Phenotypic Plasticity: Driver of Cancer Initiation, Progression, and Therapy Resistance
Understanding phenotypic plasticity is crucial for developing effective cancer therapies.
research Lymphatic Vasculature and Hair Follicle Regeneration
Lymphatic vessels help hair follicles regenerate by interacting with stem cells.
research Signaling Pathways in Hair Aging
Hair aging is caused by stress, hormones, inflammation, and DNA damage affecting hair growth and color.
research DNA Dioxygenases Tet1/2/3 Control Cell Differentiation in Hair Follicle Keratinocytes via Modulating BMP Signaling Pathway
Tet1/2/3 enzymes affect hair follicle cell development by influencing BMP signaling.
research Mature Adipocytes Inhibit the Antimicrobial Function of Dermal Adipogenic Stem Cells: An Explanation for Impaired Cutaneous Defense in Obesity
Obesity can weaken the skin's ability to fight infections because fat cells stop and reduce the infection-fighting properties of nearby stem cells.
research Hes1 Regulates Anagen Initiation and Hair Follicle Regeneration Through Modulation of Hedgehog Signaling
research Fully Functional Hair Follicle Regeneration Through the Rearrangement of Stem Cells and Their Niches
Regenerated fully functional hair follicles using stem cells, with potential for hair regrowth therapy.
research Hair Germ Model In Vitro via Human Postnatal Keratinocyte-Dermal Papilla Interactions: Impact of Hyaluronic Acid
Adding hyaluronic acid helps create larger artificial hair follicles in the lab.
research Use of Human Intra-Tissue Stem/Progenitor Cells and Induced Pluripotent Stem Cells for Hair Follicle Regeneration
Stem cells can help regenerate hair follicles.
research Skin Cell-Derived Extracellular Vesicles: A Promising Therapeutic Strategy for Cutaneous Injury
Skin cell-derived vesicles can help heal skin injuries effectively.