Dermal Microvascular Responses of Human Induced Pluripotent Stem Cell-Derived Skin Organoids to Inflammation and Injury

    February 2026 in “ American Journal Of Pathology ”
    Anthony Robert Sheets, Shannon Mary McNamee, Christine G. Lian, George H. Murphy
    Studysummary Skin organoids can mimic human skin responses to injury and inflammation, making them useful for studying skin diseases and testing treatments.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on ajp.amjpathol.org →
    Discuss this study in the Community →

    Research cited in this study 4

    1. A Skin Organoid-Based Infection Platform Identifies an Inhibitor Specific for Hand, Foot, and Mouth Disease Nature Communications · 2025
    2. Bioengineered Skin Intended as In Vitro Model for Pharmacosmetics, Skin Disease Study and Environmental Skin Impact Analysis Biomedicines · 2020
    3. Hair-Bearing Human Skin Generated Entirely From Pluripotent Stem Cells Nature · 2020
    4. Skin Wound Healing in Humans and Mice: Challenges in Translational Research Journal of Dermatological Science · 2017