Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
August 2020
in “
bioRxiv (Cold Spring Harbor Laboratory)
”
wound healing immune response electrospun membranes Random Aligned Latticed immunomodulatory ability fibrotic response cutaneous appendages skin wound repair Single-cell RNA sequencing hair follicle progenitor cells inner root sheath cells anagen fibroblast subsets hair follicle regeneration wound closure macrophages neutrophils effector T cells adaptive immunity microenvironment cutaneous cells
Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.
Studysummary This study found that electrospun membranes with aligned surface topography enhanced wound healing and hair follicle regeneration while modulating the immune response in a mouse skin wound model.
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