January 2025 in “PLoS ONE” This study found that aligned electrospinning membranes enhance skin wound healing by upregulating MMP12 expression and inhibiting fibroblast migration, which results in reduced scar formation, providing valuable insights for developing more effective biological dressings.
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January 2022 in “Biomaterials Science” This study found that bioinspired conductive dressings with aligned wrinkles can monitor joint motion and significantly accelerate wound healing in mice by promoting collagen deposition, hair follicle regeneration, and epithelialization.
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April 2025 in “Materials Today Communications” In this study, researchers developed a composite electrospun dressing with fiber gradient changes that mimics skin's natural structure, demonstrating enhanced wound healing, collagen deposition, and reduced fibrosis and scarring in both in vitro and in vivo experiments.
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February 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that electrospinning membranes with smaller fiber diameters significantly improved skin wound healing by promoting cell proliferation and encouraging reparative macrophage transformation.
This study reports that in a rat model of myocardial infarction, Zn-Cu ion sequential therapy improved cardiac function and cardiomyocyte metabolic activity by precisely regulating ion concentrations and maintaining elevated levels of the Per2 protein, important for cellular repair.