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GlossaryPlasma Cells (Effector B Cells)

cells that produce antibodies to fight infections

Plasma cells, also known as plasma B cells or effector B cells, are a type of white blood cell that originates from B lymphocytes. Their primary function is to produce and secrete large quantities of antibodies, which are proteins that help the immune system identify and neutralize pathogens like bacteria and viruses.

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Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

research Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1

1 citations, May 2022 in “Frontiers in Pharmacology”

Astilbin can potentially calm overactive immune responses, like in Type 1 Diabetes, by suppressing certain cell activities and reducing inflammation.

research Th22 Is the Effector Cell of Thymosin β15-Induced Hair Regeneration in Mice

January 2024 in “Inflammation and regeneration”

Th22 cells are essential for Tβ15-induced hair growth in mice.

research Malt1 Protease Is Critical in Maintaining Function of Regulatory T Cells and May Be a Therapeutic Target for Antitumor Immunity

39 citations, April 2019 in “The journal of immunology/The Journal of immunology”

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata

64 citations, July 2016 in “Journal of Immunology”

Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.

research Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata

13 citations, September 2022 in “Frontiers in immunology”

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

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community Creatine's effect on Hair Loss and DHT

in Research/Science 102 upvotes 9 months ago

A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

community 6 months on topical Minoxidil + Finasteride

in Progress Pictures 58 upvotes 4 months ago

User has been using topical Minoxidil (5%) and Finasteride (0.1%) for 5-6 months, along with a dermaroller. No side effects reported, but user notes weight gain without change in diet or exercise.

community Alright boys, who’s willing to burn their scalp for science?

in Research/Science 765 upvotes 1 year ago

Researching the effects of scalp trauma on hair growth, with some users suggesting experimenting with a soldering iron or derma pen, and others bringing up studies that suggest this may be an effective treatment.

community So we have 20k dollars human like machines available but no new effective treatment for hairloss since finasteride :)

in Chat 237 upvotes 2 months ago

There have been no new effective hair loss treatments since finasteride, despite technological advancements. Current treatments include finasteride, minoxidil, and RU58841, with ongoing challenges and potential future solutions in research.

community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

in Treatment 6 upvotes 4 years ago

Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

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