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    Glossary Inner Root Sheath

    layer of cells supporting and shaping the growing hair shaft

    The Inner Root Sheath (IRS) is a layer of cells that surrounds and supports the growing hair shaft within the hair follicle. It plays a crucial role in shaping the hair and guiding it as it emerges from the scalp. The IRS is composed of three distinct layers: Henle's layer, Huxley's layer, and the cuticle of the inner root sheath, each contributing to the structural integrity and function of the hair follicle.

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    Research 10 of 1000+

    1. Structural features of the α-type filaments of the inner root sheath cells of the guinea pig hair follicle Biochemistry · 1978 · 24 citations
    2. Cytochemistry of Trichohyalin Granules: A Possible Role for Cornification of Inner Root Sheath Cell in the Hair Follicle The Journal of Dermatology · 1989 · 4 citations
    3. A Novel Epithelial Keratin, hK6irs1, is Expressed Differentially in All Layers of the Inner Root Sheath, Including Specialized Huxley Cells (Flügelzellen) of the Human Hair Follicle Journal of Investigative Dermatology · 2002 · 86 citations
    4. Keratins 1 and 10 or homologues as regular constituents of inner root sheath and cuticle cells in the human hair follicle. PubMed · 1990 · 44 citations
    5. μ-Crystallin, Thyroid Hormone-binding Protein, is Expressed Abundantly in the Murine Inner Root Sheath Cells Journal of Investigative Dermatology · 2000 · 22 citations
    6. Keratinization of outer root sheath cells is prevented by contact with inner root sheath of rat hair follicles Archives of Dermatological Research · 2008 · 9 citations
    7. Some observations on the proteins of the inner root sheath cells of hair follicles Biochimica et Biophysica Acta · 1958 · 34 citations
    8. A novel monoclonal antibody to the outer root sheath cells Journal of Dermatological Science · 1994 · 3 citations
    9. 889 Trpv3 gain-of-function mutation impairs differentiation of hair follicle inner root sheath 2019
    10. Abnormal inner root sheath of the hair follicle in the loose anagen hair syndrome: An ultrastructural study Journal of the American Academy of Dermatology · 2010 · 31 citations
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    Community 1 of 2

    1. Topical Finasteride Doesn't Directly Reduce 5ar Enzyme on Scalp Reddit · 19 May 2023
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