Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This review examines recent advancements in green and emerging microextraction techniques, such as SPME and DLLME, for more sustainable hormone detection in biological samples, emphasizing environmentally friendly solvents and bioanalytical applications.

In this study, researchers optimized the extraction conditions for polyphenols from the medicinal herb Eclipta prostrata, achieving the highest polyphenol content under specific conditions of temperature, solvent concentration, and time, and found the extract to have significant antioxidant activity.

This study demonstrated that imidazole-based ionic liquids, particularly [Emim]DEP, effectively dissolved yak hair keratin, maintaining its structure better than other tested solvents, and also performed well on human hair and goat wool, with consistent performance even after five recycling cycles.

This study identified two potent 5α-reductase inhibitors from Tectona grandis leaves, and suggests that ethanol is a preferable solvent for extracting these compounds, which are potential ingredients for hair loss treatments.

This study introduced new spectrophotometric methods to estimate Minoxidil in pharmaceutical forms, demonstrating its linearity across various buffers and solvents, and found these methods to be simple, economical, and effective according to ICH guidelines.

In this study, methanolic extracts of Hibiscus rosa-sinensis showed higher phenolic and flavonoid content, as well as greater concentrations of gallic acid and quercetin, than aqueous extracts, despite the latter yielding more extract, highlighting the effectiveness of methanol for extracting bioactive phytochemicals.

This study concluded that rosemary essential oil rich in terpenes was successfully extracted using vacuum-assisted hydrodistillation, and Solid Phase Micro Extraction was superior for identifying volatile compounds compared to direct injection.

This study suggests that melatonin may have a radioprotective role against X-ray-induced skin damage in rats, as evidenced by milder injury markers in pretreated animals.

This study found a strong correlation between antioxidant activity and phenolic content in rosemary, influenced by bioclimatic and seasonal factors in different stages of Tunisia.

A fatty acid/protein complex in human hair helps protect it from damage.

This study found that the imidacloprid/flumethrin collar (Seresto®) is chemically compatible with major spot-on formulations and dermally and systemically safe for adult dogs and cats when used together.

In this study, researchers investigated EGCG's spectroscopic properties and its interaction with DPPG lipid, finding that both experimental and theoretical approaches agree on the electronic transitions and reveal an increased absorbance due to molecular interactions.

This study reported that meloxicam-loaded spanlastics, created using the ethanol injection method, demonstrated potential as a drug delivery system with sustained release and effective entrapment efficiency.

This study found that chitin nanofibrils prepared by the aqueous counter collision process exhibited superior emulsifying properties for stabilizing oil droplets in Pickering emulsions compared to cellulose nanofibrils.

This study found that under optimized extraction conditions, the Gleditschia fera fruit extract contained a high level of saponins and demonstrated notable antioxidant activity.

This study developed a straightforward HPTLC method for detecting nicotine and cotinine in human plasma and urine, concluding that liquid-liquid extraction with methanol: chloroform: ammonia achieved optimal separation and is applicable for forensic analysis of lethal nicotine intoxication.

This study found that Mitracarpus hirtus extracts showed potential antifungal activity against Tinea capitis in vitro, with ethylacetate extracts demonstrating the highest inhibitory effects.

Using K2S2O8 as an oxidizing agent in a specific condition, we can make Finasteride with 96.3% yield and 99.6% purity. This method is also good for other compounds and is environmentally friendly.

In this study, the researchers developed and evaluated a Minoxidil emulgel formulation, finding that it had a higher drug release rate compared to Minoxidil gels.

This study demonstrated that the IVL-DrugFluidic® platform is effective for mass-producing finasteride-loaded polymeric microspheres for long-acting injectables, maintaining stable drug release without an initial burst for a month.

This study found that melatonin may enhance hair growth properties in dermal papilla cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors.

This study developed an accurate and reliable HPLC-ESI-MS method for determining candesartan levels in human plasma, useful for pharmacokinetic studies.

Chitosan-coated nanocapsules improve minoxidil delivery for better hair regrowth.

This study on albino mice found that hair tonic formulations using methanolic and ethanolic extracts of Beta vulgaris L. promoted hair growth, with the ethanolic extract showing greater effectiveness in terms of length and diameter, potentially due to antioxidant and anti-inflammatory effects.

This study analyzed the bioactive compound profiles of Allium longisepalum from Iran, finding unique metabolites with potential antioxidant, allelopathic, antibacterial, anti-inflammatory, anticarcinogenic, and hair growth-enhancing properties, revealing the plant's chemical diversity and therapeutic potential.

This study explored the solubility and crystal structure of GI197111X, a 5-alpha reductase inhibitor for androgenetic alopecia, finding its solubility in Capmul MCM suitable for a soft gel dosage form.

This study found that preparing finasteride as a nanosuspension increased its aqueous solubility by more than 2.5 times, potentially enhancing drug bioavailability.

This study developed a precise and simple HPLC method for estimating tamsulosin and finasteride simultaneously in pharmaceutical forms, demonstrating good precision and potential usefulness for combined dosage analysis.

This review discusses strategies for developing semi-solid topical generic products to match the quality of reference-listed drugs, using concepts like quality by design and reverse-engineering, but reports no new results.

This review examines dermatological side effects of taxane chemotherapy reported in past studies and highlights the necessity for identifying and managing these conditions to maintain cancer patients' quality of life; it presents no new clinical results.