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Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Lactate production is important for activating hair growth stem cells.

Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Essential oils in cosmetics can offer benefits but may cause allergies and should be used carefully.

Androgens can help prevent memory problems caused by apoE4.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

The new "differential stripping" method effectively measures how much substance gets into hair follicles.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.

Alopecia areata causes hair loss, has no cure, and various treatments exist.

Androgens, like testosterone, are crucial for early testicular descent in rats.

Taxane chemotherapy can cause skin, hair, and nail side effects, which are often under-reported and can affect patient quality of life.

Hair follicles may soon be used more for targeted and systemic drug delivery.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Microneedles improve drug delivery in various body parts, are safe and painless, and show promise in cosmetology, vaccination, insulin delivery, and other medical applications.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Minoxidil promotes hair growth in male pattern baldness.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Gene therapy with the Math1 gene helped regenerate balance-related cells and improve balance in mice.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Finasteride effectively treats baldness but may cause sexual side effects.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Targeting androgen receptors could be a promising way to treat skin disorders with fewer side effects.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.