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March 2019 in “Experimental dermatology” Activating TLR3 may help produce retinoic acid, important for tissue regeneration.
5 citations,
June 2015 in “Journal of Investigative Dermatology” Feathers are useful for researching growth, regeneration, and the effects of treatments like chemotherapy on hair loss.
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April 2023 in “Science Advances” High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
1 citations,
January 2018 in “Recent clinical techniques, results, and research in wounds” Using developmental signaling pathways could improve adult wound healing by mimicking scarless embryonic healing.
1 citations,
July 2010 in “Dermatologic Surgery” Splitting one hair follicle into two can help regrow hair with a 50% to 70% success rate, useful when donor hair is limited.
August 2023 in “Molecules and Cells” Hair can regrow after significant damage through a process similar to how it forms before birth, involving stem cells and various cell types and signals. This could be a new way to prevent scarring and promote hair growth.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
Boosting certain cell signals can prevent hair loss from chemotherapy and radiation.
June 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A specific molecular switch, driven by MAPK/ERK signaling, helps spiny mice heal wounds by regenerating skin instead of forming scars.
May 2018 in “Cell stem cell” Myoepithelial cells can repair airways after severe injury.
April 2015 in “Plastic and Reconstructive Surgery” Activating TLR3 helps improve skin and hair follicle regeneration after wounds.
April 2012 in “Annals of Neurosciences” The document concludes that stem cell therapies lack solid proof of effectiveness, except for blood system treatments, and criticizes the ethical issues and commercial exploitation in the field.
August 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” A new method using special materials can help regrow hair by creating small wounds.
April 2024 in “Journal of asthma and allergy” Abrocitinib effectively treated severe atopic dermatitis and mild alopecia areata in a 12-year-old boy after dupilumab failed.
October 2023 in “Journal of Molecular Liquids” A new method using imidazole-based liquids efficiently extracts keratin from yak hair.
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August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
499 citations,
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321 citations,
March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
321 citations,
December 2009 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
235 citations,
January 2011 in “Journal of Clinical Investigation” Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.
202 citations,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
169 citations,
February 2018 in “Immunity” Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
145 citations,
November 2018 in “Nature Communications” The Sonic hedgehog pathway is crucial for new hair growth during mouse skin healing.
138 citations,
June 2019 in “Stem Cells and Development” Periodontal ligament stem cells show promise for regrowing tissues but require more research for safe, effective use.
133 citations,
September 2013 in “Nature Reviews Molecular Cell Biology” Different types of stem cells and their environments are key to skin repair and maintenance.
115 citations,
March 2001 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Key enzymes control androgen levels, affecting hormone activity and potential treatments.
84 citations,
January 2018 in “Biomaterials Science” Sericin hydrogels heal skin wounds well, regrowing hair and glands with less scarring.
81 citations,
July 2008 in “The Journal of Clinical Endocrinology and Metabolism” Certain mutations in the H6PD gene cause Cortisone Reductase Deficiency by affecting hormone production.
78 citations,
October 2012 in “Biomaterials” Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
73 citations,
July 1956 in “Journal of Investigative Dermatology” Adult human skin can grow new fine hair follicles after a deep exfoliation treatment.