Follicular Bisection in Hair Restoration: In Vivo Experiment

    September 2010 in “ Dermatologic Surgery
    Alfredo De Rossi, Michele Gilio, Giuseppe Pistola, Marta Carlesimo, Riccardo Borroni, Maria Caterina Fortuna, Marco Toscani
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    TLDR Splitting one hair follicle into two can help regrow hair with a 50% to 70% success rate, useful when donor hair is limited.
    In a study conducted 13 years ago, 21 healthy men aged 26 to 51 with androgenetic alopecia were subjected to a hair restoration technique called follicular bisection. This technique involves the transection of one follicular unit (FU) into two growing follicles to regenerate new hairs. The study aimed to evaluate the survival and growth rates of horizontally bisected hair grafts. The results showed a 50% to 70% regrowth rate from bisected hairs, consistent with previous studies. The hair caliber obtained from the shaft was similar to the original, whereas the one obtained from the bulb was thinner and showed scant pigmentation. The study concluded that in cases of limited donor area, this technique may be helpful as hairs generated from the upper or lower portion of a bisected FU possess a similar rate of regrowth.
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