This study found that ethanolic plant extract of Peperomia pellucida increased hair length in rabbits in a dose-dependent manner but did not significantly affect hair mass compared to controls.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” In this study, a new hair serum featuring Catharanthus roseus extract was formulated and evaluated, showing a stable and appealing product with potential hair growth-promoting properties, positioning it as a promising herbal alternative to synthetic agents like minoxidil.
5 citations
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June 2018 in “Records of Natural Products” This study found that Lepidium sativum leaf extract significantly downregulated VEGF, TNF-α, and SRD5A2 gene expressions in HaCaT cells, suggesting potential benefits for inflammatory and androgen-dependent skin disorders.
7 citations
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September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” This study reports the successful formulation of a stable herbal hair serum with Catharanthus roseus extract and other ingredients, noting it has a suitable pH, consistency, and stability, suggesting potential effectiveness as a natural alternative for hair care pending further clinical trials.
August 2023 in “Skin Research and Technology” In this clinical trial, oral consumption of a persimmon leaf extract-containing complex significantly increased hair density and thickness over 24 weeks compared to a placebo, although improvements in hair gloss were not statistically significant.
8 citations
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September 2017 in “Journal of Natural Medicines” This study reported that the n-butanol fraction of Perilla frutescens extract, particularly rosmarinic acid, showed potential for hair regrowth and anti-androgenic activity in male mice, suggesting it as a possible treatment for androgenetic alopecia.
5 citations
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March 2023 in “Journal of Cosmetic Dermatology” This study reports that Plantago asiatica L. extract may promote hair growth by enhancing growth factor production and activating specific signaling pathways in hair follicle dermal papilla cells.
November 2024 in “Journal of Cosmetic Dermatology” This study observed that a topical serum containing Silybum marianum extract, manganese PCA, and Lespedeza capitata extract enhanced hair follicle growth and hair shaft elongation, while prolonging the anagen phase in an ex vivo human scalp skin model, suggesting potential benefits for hair loss treatment.
September 2019 in “Journal of Investigative Dermatology” This study found that a combination of botanical extracts from Pisum sativum and Salvia hispanica reduced oxidative damage, re-balanced scalp oiliness, and improved scalp hydration and barrier function after pollution exposure.
This study examined the use of Purwaceng extract in shampoo formulations, concluding that a specific formula (Sample F1) showed good stability and safety, suggesting its potential effectiveness for hair health issues like dandruff and hair loss.
1 citations
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October 2017 This study found that topical gel containing ethanolic extract of Peperomia pellucida increased hair length in rabbits, but did not significantly impact hair mass compared to control treatments.
January 2002 in “Journal of Toxicology-cutaneous and Ocular Toxicology” Botanical extracts are increasingly important in cosmetics and drugs for their effectiveness and safety, backed by traditional use and scientific evidence.
2 citations
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January 2022 in “Journal of Oleo Science” This study found that oil from CG17 garden cress seeds had higher amounts of β-carotenoids, tocopherols, and vitamins compared to other genotypes, with varying physiochemical properties across all seeds.
3 citations
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April 2023 in “Quality Assurance and Safety of Crops & Foods” This study found that oil extracted from Prinsepia utilis seeds is physicochemically stable and suitable for use in manufacturing ketoconazole soap, which met quality control standards and may provide a cost-effective alternative to expensive additives in cosmetic and pharmaceutical applications.
May 2026 in “Applied Sciences” In this review, the authors reported that sprout extracts, rich in bioactive compounds, show promising effects on skin health, such as enhancing collagen synthesis, improving hydration, and reducing inflammation, though most evidence comes from laboratory and animal studies.
21 citations
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June 2022 in “Molecules” This review discusses the phytochemistry and pharmacological activities of Perilla frutescens, detailing its bioactive compounds and their potential health benefits, but reports no new clinical results.
18 citations
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February 2024 in “Nutrients” This study investigated a novel extract from pomegranate byproducts, finding it effective in reducing blood pressure and inflammation in hypertensive rats, comparable to Captopril, while also highlighting the extract's potential to enhance the pomegranate supply chain and environmental benefits.
14 citations
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April 2021 in “Heliyon” This study found that both alcoholic and aqueous extracts of Punica granatum L. showed potential for promoting hair growth and exhibited anti-lice and antidandruff activities in a mouse model.
3 citations
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November 2022 in “Molecules/Molecules online/Molecules annual” This study found that ingesting Lactobacillus paracasei HY7015 and Lycopus lucidus Turcz. extract promoted hair regrowth and follicle maturation in mice by enhancing cytoprotective effects and growth factor expression.
14 citations
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June 2024 in “Food Chemistry X” This review highlights that pomegranate leaf exhibits potential health benefits, such as anti-cancer, anti-diabetic, anti-inflammatory, and neuroprotective effects in vitro and in animal models, but calls for comprehensive human clinical trials to confirm these therapeutic benefits and ensure safety.
1 citations
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March 2019 in “Journal of Drug Delivery and Therapeutics” This study found that petroleum ether extract of Abrus precatorius leaves at 300 mg/kg promoted hair growth in animal models similarly to 2% minoxidil.
This study found that supercritical fluid extraction of germinated perilla seed significantly promoted hair follicle cell proliferation and gene expression related to hair growth, suggesting its potential as a natural treatment for hair loss.
January 2018 in “BiblioBoard Library Catalog (Open Research Library)” 21 citations
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January 2020 in “Pharmaceutical Biology” In this study, Salvia plebeia extract promoted hair growth by enhancing proliferation and anti-apoptotic effects in human dermal papilla cells and increased hair growth in treated mice.
13 citations
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May 2019 in “Cancer Prevention Research” This study found that a three-month regimen of leucoselect phytosome, a grape seed extract complex, was well tolerated and significantly reduced bronchial proliferation markers in heavy active and former smokers.
April 2022 in “Jurnal Penelitian Farmasi dan Herbal” In this study, hair tonic containing 15% patchouli leaf extract showed the greatest hair growth in rabbits, with higher concentrations leading to faster regrowth.
6 citations
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December 2022 in “Toxicological Research” June 2022 in “Journal of Cosmetic Dermatology” This study found that the ethanolic extract of Acanthus ebracteatus demonstrated potential as an anti-hair loss treatment by promoting dermal papilla cell proliferation, inhibiting 5α-reductase activity, and reducing inflammation in vitro.
1 citations
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January 2022 in “Journal of Oleo Science” This study found that an aqueous extract of Phyllanthus emblica, primarily containing gallic acid, can activate hair growth gene expression and is effectively delivered to hair follicles using transfersomes.