April 2023 in “Dentistry” Baby teeth stem cells can potentially grow organs and treat diseases.
January 2023 in “Biomedicine & Pharmacotherapy” Low oxygen conditions improve how well certain stem cells from embryos can make hair grow longer and faster.
January 2023 in “Biomaterials Science” Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
August 2022 in “Biomedicines” Turning off the Lhx2 gene in mouse embryos leads to slower wound healing and scars.
January 2017 in “Journal of Investigative Dermatology Symposium Proceedings” The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.
January 2014 in “Indian dermatology online journal” Different treatments help heal leg ulcers depending on their type, with new therapies showing promise for chronic wounds.
Stem cell treatments show promise for hair loss but need more research.
March 2023 in “International Journal of Molecular Sciences” ADSC-Exos with miR-122-5p can help treat hair loss by promoting hair growth.
December 2022 in “Molecular Pharmaceutics” Latanoprost-loaded nanotransfersomes could help treat hair loss by promoting hair growth.
November 2022 in “Regenerative Therapy” Advancements in tissue engineering show promise for hair follicle regeneration to treat hair loss.
November 2022 in “Annals of Translational Medicine” Immune activities and specific genes are important in male pattern baldness.
41 citations,
January 2020 in “BioMed Research International” Micrografts improve hair density and thickness without side effects.
65 citations,
April 2020 in “International Journal of Molecular Sciences” PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
9 citations,
August 2021 in “Biological Chemistry” ECM-inspired wound dressings can help heal chronic wounds by controlling macrophage activity.
9 citations,
May 2021 in “Immunological Reviews” Different types of fibroblasts play various roles in kidney repair and aging, and may affect chronic kidney disease outcomes.
7 citations,
August 2020 in “Genes” Different genes are active in dogs' hair growth and skin, similar to humans, which helps understand dog skin and hair diseases and can relate to human conditions.
January 2022 in “Stem cell biology and regenerative medicine” The document concludes that hair follicle regeneration involves various factors like stem cells, noncoding dsRNA, lymphatic vessels, growth factors, minoxidil, exosomes, and induced pluripotent stem cells.
September 2023 in “Cureus” Topical finasteride might be a good alternative for hair loss treatment with fewer side effects, but more research is needed.
17 citations,
February 2019 in “PubMed” Stem cells can help regenerate hair follicles.
21 citations,
November 2017 in “Scientific Reports” Different human hair follicle stem cells grow at different rates and respond differently to a baldness-related compound.
50 citations,
September 2014 in “Stem cell reports” BLIMP1 is essential for skin maintenance but not for defining sebaceous gland progenitors.
57 citations,
January 2014 in “Cold Spring Harbor Perspectives in Medicine” Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.
29 citations,
June 2018 in “Scientific Reports” 15-lipoxygenase helps keep skin healthy by reducing inflammation.
12 citations,
August 2016 in “Current opinion in genetics & development” Organs like hair follicles can renew themselves in complex ways, adapting to different needs and environments.
1 citations,
January 2013 in “Journal of Investigative Dermatology” The document concludes that stem cells and their environments are crucial for skin and hair health and have potential for medical treatments.
April 2017 in “Journal of Investigative Dermatology” Sirolimus and propranolol may reduce abnormal cell growth and improve lymphatic malformations in children.
1 citations,
January 2023 in “In vivo/In Vivo” Box A of HMGB1 can improve stem cell function, aiding anti-aging therapy.
2 citations,
May 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Stem cells help remove dead cells to keep tissues healthy by balancing cell replacement and clearance.
130 citations,
March 2014 in “Proceedings of the National Academy of Sciences of the United States of America” Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
18 citations,
August 2017 in “PLOS ONE” Skin and its underlying fat layer act together to resist mechanical stress, and reinforcing this composite structure may help more with anti-aging than just strengthening the skin alone.